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Cardinals vs Reds Odds, Probable Pitchers, Betting Lines, Spread & Prediction for MLB Opening Day Game

Larry Rupp
Cardinals vs Reds odds, probable pitchers, betting lines, spread & prediction for MLB game.
Cardinals vs Reds odds, probable pitchers, betting lines, spread & prediction for MLB game. / Michael Reaves/Getty Images
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Cardinals vs Reds Game Info

St. Louis Cardinals (0-0, 0-0 Away) vs. Cincinnati Reds (0-0, 0-0 Home)
Date: Thursday, April 1, 2021
Time: 4:10 p.m. EST
Venue: Great American Ball Park – Cincinnati, OH

Cardinals vs Reds Betting Info

All MLB betting lines, odds, and spreads are according to FanDuel Sportsbook.
Moneyline: STL: (+100) | CIN: (-118)
Spread: STL: -1.5 (+176) | CIN: +1.5 (-210)
Total: 7.5 – Over: (+100) | Under: (-122)
Public (Spread) Betting Percentages (via Oddsfire): STL: (56%) | CIN: (44%)
World Series Odds: STL: (+2200) | CIN: (+3500)

Cardinals vs Reds Probable Pitchers

Cardinals: Jack Flaherty (0-0, 0.00 ERA)
Reds: Luis Castillo (0-0, 0.00 ERA)

Cardinals vs Reds Expert Prediction & Pick

All MLB predictions & expert picks are according to CBS Sports.
Winner: St. Louis Cardinals
Over/Under: Over 7.5

Cardinals vs Reds Betting Trends

- St. Louis is 10-5 in its last 15 games against Cincinnati.
- The total has hit the over in four of St. Louis' last five road games.
- Cincinnati is 8-2 straight up in its last 10 home games.
- The total has hit the under in six of Cincinnati's last seven games against a National League opponent.

Cardinals vs Reds Stats

- St. Louis averaged 4.20 runs per game last season (No. 24 in MLB).
- St. Louis surrendered 4.07 runs per game last season (No. 7 in MLB).
- Cincinnati averaged 3.92 runs per game last season (No. 28 in MLB).
- Cincinnati surrendered 4.02 runs per game last season (No. 6 in MLB).


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Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

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