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49ers vs Eagles Prediction, Odds, Spread, Over/Under & Betting Trends for NFL Week 2 Game on FanDuel Sportsbook

Larry Rupp
San Francisco 49ers vs Philadelphia Eagles prediction, odds, spread, over/under and betting trends for NFL Week 2 Game.
San Francisco 49ers vs Philadelphia Eagles prediction, odds, spread, over/under and betting trends for NFL Week 2 Game. / Christian Petersen/Getty Images
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49ers vs Eagles Week 2 Game Info

NFL Regular Season — Week 2 Game
San Francisco 49ers (1-0, 1-0 Away) vs. Philadelphia Eagles (1-0, 0-0 Home)
Date: Sunday, September 19, 2021
Time: 1:00 p.m. EST
Venue: Lincoln Financial Field — Philadelphia, PA
Coverage: FOX

49ers vs Eagles Odds & Spread

All NFL regular betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: SF: (-156) | PHI: (+132)
Spread: SF: -3 (-106) | PHI: +3 (-114)
Total: 49.5 — Over: (-105) | Under: (-115)
Public (Spread) Betting Percentages via oddsFire: SF: (N/A) | PHI: (N/A)
Odds to Win Super Bowl LVI: SF: (+1300) | PHI: (+7000)

49ers vs Eagles Prediction & Pick

All NFL predictions and picks are from numberFire's projection model.
Prediction: 49ers win (64.8%)

49ers vs Eagles Betting Trends

- San Francisco is 0-1 against the spread (ATS) this season.
- The total hit the over in San Francisco's first game this season.
- Philadelphia is 1-0 ATS this season.
- The total hit the under in Philadelphia's first game this season.


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Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

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