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Tigers vs Guardians Prediction, Odds, Probable Pitchers, Betting Lines & Spread for MLB Game (May 21)

Devon Platana
Detroit Tigers vs Cleveland Guardians prediction, odds, probable pitchers, betting lines & spread for MLB game.
Detroit Tigers vs Cleveland Guardians prediction, odds, probable pitchers, betting lines & spread for MLB game. / David Richard-USA TODAY Sports
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Tigers vs Guardians Game Info

2022 MLB Regular Season Game
Detroit Tigers (13-26, 4-13 Away) vs. Cleveland Guardians (17-19, 8-7 Home)
Date: Saturday, May 21, 2022
Time: 6:10 p.m. ET
Venue: Progressive Field — Cleveland, OH

Tigers vs Guardians Odds & Spread

All MLB odds, totals and spreads are according to FanDuel Sportsbook.
Moneyline: DET: (+160) | CLE: (-190)
Spread: DET: +1.5 (-137) | CLE: -1.5 (+114)
Total: 8 – Over: (-110) | Under: (-110)
World Series Odds: DET: (+25000) | CLE: (+8000)

Tigers vs Guardians Probable Pitchers

Tigers: Alex Faedo (0-1, 2.87 ERA)
Guardians: Shane Bieber (1-2, 3.72 ERA)

Tigers vs Guardians Expert Prediction & Pick

All MLB predictions & expert picks are according to numberFire.
Prediction: Cleveland Guardians win (66.7%)

Tigers vs Guardians Betting Trends

- Detroit is 5-15 straight up in its last 20 road games against Cleveland.
- Cleveland is 8-3 straight up in its last 11 games against AL Central opponents.
- The total has hit the under in 12 of Detroit's last 16 games.
- The total has hit the over in four of Cleveland's last five games against Detroit.

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Devon Platana is not a FanDuel employee. In addition to providing DFS gameplay advice, Devon Platana also participates in DFS contests on FanDuel using his personal account, username PepeSilvia0. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.

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