Jaguars vs Colts Point Spread, Over/Under, Moneyline and Betting Trends for NFL Week 10 Game

Week 10's slate of games includes a showdown between the Jacksonville Jaguars and Indianapolis Colts.

Here's everything you need to know before placing your bet for this game on FanDuel Sportsbook.

Jaguars vs Colts Point Spread

The Colts are 10.5-point home favorites against the Jaguars. Indianapolis is -105 to cover the spread, while Jacksonville is -115 to cover as a 10.5-point underdog.

Jaguars vs Colts Over/Under

The over/under for the Jaguars vs Colts Week 10 NFL matchup is set at 47.5, with -110 odds on the over and -110 odds on the under.

Jaguars vs Colts Moneyline

The Jaguars vs Colts moneyline has Indianapolis as a -480 favorite, while Jacksonville is a +370 underdog on the road.

Jaguars vs Colts Betting Trends

- Jacksonville is 4-8 against the spread (ATS) in its last 12 games.
- The total has hit the under in six of Jacksonville's last seven games.
- Indianapolis is 5-1 ATS in its last six games.
- The total has hit the over in five of Indianapolis' last six games.

Jaguars vs Colts Prediction

All NFL predictions and picks are from numberFire's projection model.
Prediction: Indianapolis Colts win (81.2%)

Jaguars vs Colts Odds

All NFL regular betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: JAX: (+370) | IND: (-480)
Spread: JAX: +10.5 (-110) | IND: -10.5 (-110)
Total: 47.5 — Over: (-110) | Under: (-110)
Odds to Win Super Bowl LVI: JAX: (+100000) | IND: (+7000)

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Max Staley is not a FanDuel employee. In addition to providing DFS gameplay advice, Max Staley also participates in DFS contests on FanDuel using his personal account, username mstaley1212. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.