DePaul vs Louisville Prediction, Odds, Spread, Line & Over/Under for Dec. 10 College Basketball Game

DePaul vs Louisville Basketball Game Info

DePaul Blue Demons (7-1, 0-0 Away) vs. Louisville Cardinals (6-2, 3-1 Home)
Date: Friday, December 10, 2021
Time: 8 p.m. EST
Venue: KFC Yum! Center — Louisville, KY
Coverage: ACCN

DePaul vs Louisville Spread & Odds

All NCAAM betting lines, odds and prop bets are available on FanDuel Sportsbook.
Moneyline: DEP: (+280) | LOU: (-360)
Spread: DEP: +7.5 (-110) | LOU: -7.5 (-110)
Total: 147 – Over: (-110) | Under: (-110)
Odds to Win NCAAM National Championship: DEP: (+29000) | LOU: (+8000)

DePaul vs Louisville Prediction & Pick

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Louisville Cardinals win (73.8%)

DePaul vs Louisville Head-to-Head Results & Betting Trends

- Louisville is 38-21 in 59 all-time head-to-head matchups against DePaul.
- Louisville defeated DePaul, 79-58, in their last meeting on Feb. 27, 2013.
- DePaul is 0-10 straight up in its last 10 games against Louisville.
- Louisville is 6-3 against the spread (ATS) in its last nine games as the favorite.
- DePaul is 7-1 ATS in its last eight games.
- The total has hit the under in seven of Louisville's last 10 games against DePaul.

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Devon Platana is not a FanDuel employee. The views expressed in his articles are the author's alone and do not necessarily reflect the views of FanDuel.