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Full Cardinals 2021 Schedule: List of Arizona Opponents This NFL Season

Larry Rupp
Arizona Cardinals football schedule for the 2021 NFL season.
Arizona Cardinals football schedule for the 2021 NFL season. / Sean M. Haffey/Getty Images
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The 2021 NFL schedule release is fast approaching on May 12. The Arizona Cardinals will have to fight hard if they want to come out on top of a very tough NFC West division in 2021.

2021 Cardinals Schedule

Here's everything we know so far about the Cardinals' schedule in 2021.

Arizona Cardinals Football Schedule 2021

Cardinals Week 1 Opponent

The Arizona Cardinals' Week 1 matchup has been officially revealed. They will open the season with a road game against the Tennessee Titans on Sunday September 12, 2021.

Cardinals 2021 Strength of Schedule

According to ESPN's Mike Clay, the Cardinals have the 11th-hardest schedule in the NFL for 2021.

Cardinals Home Games 2021

- Los Angeles Rams
- San Francisco 49ers
- Seattle Seahawks
- Green Bay Packers
- Minnesota Vikings
- Houston Texans
- Indianapolis Colts
- Carolina Panthers

Cardinals Away Games 2021

- Los Angeles Rams
- San Francisco 49ers
- Seattle Seahawks
- Chicago Bears
- Dallas Cowboys
- Detroit Lions
- Jacksonville Jaguars
- Tennessee Titans
- Cleveland Browns

Cardinals Opponents Record 2021

The Cardinals' opponents went 138-134 during the 2020 NFL season.

Cardinals 17th Game Opponent

The NFL has added an extra 17th game to the 2021 season, which will pit the Cardinals against the Cleveland Browns.

Cardinals Super Bowl Odds

The Cardinals currently have the 18th-best odds on FanDuel Sportsbook to win the Super Bowl in 2021 at +4000.


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Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

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