Cover Photo: Ethan Miller/Getty Images

When it comes to handicapping Week 1 games, even the pros have trouble picking winners and losers.

Some like home teams and the so-called "home-field advantage" should be even greater with fans coming out in full swing for the season opener. And some like road teams, since the rigors of travel won't affect the road team like it does as the season progresses.

But, looking at the numbers, playing at home or playing on the road means absolutely nothing when it comes to beating a spread in the NFL. 

So when you sit down to make your against-the-spread picks this week, remember it's a 50-50 proposition over the past 10 seasons. 

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