NFL - Odds & Predictions

Patriots vs Bills Prediction, Odds, Spread, Over/Under & Betting Trends for NFL Week 13 Monday Night Football

Jason Schandl
New England Patriots vs Buffalo Bills prediction, odds, spread, over/under and betting trends for NFL Week 13 game.
New England Patriots vs Buffalo Bills prediction, odds, spread, over/under and betting trends for NFL Week 13 game. / Don Juan Moore/GettyImages
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Patriots vs Bills Week 13 Game Info

NFL Regular Season — Week 13 Monday Night Football
New England Patriots (8-4, 5-0 Away) vs. Buffalo Bills (7-4, 3-2 Home)
Date: 
Monday, December 6, 2021
Time: 8:15 p.m. EST
Venue: Highmark Stadium — Orchard Park, NY
Coverage: ESPN

Patriots vs Bills Odds & Spread

All NFL betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: NE: (+120) | BUF: (-142)
Spread: NE: +2.5 (-105) | BUF: -2.5 (-115)
Total: 43.5 — Over: (-110) | Under: (-110)
Odds to Win Super Bowl LVI: NE: (+1100) | BUF: (+800)

Patriots vs Bills Prediction & Pick

All NFL predictions and picks are from numberFire's projection model.
Prediction: Buffalo Bills win (65.7%)

Patriots vs Bills Betting Trends

- New England is 6-0 against the spread (ATS) in its last six games.
- The total has hit the over in six of New England's last eight games.
- Buffalo is 13-6-1 ATS in itsl ast 20 games.
- Buffalo is 4-0-1 ATS in its last five games against AFC East opponents.


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Jason Schandl is not a FanDuel employee. In addition to providing DFS gameplay advice, Jason Schandl also participates in DFS contests on FanDuel using his personal account, username Jaymun. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in his articles are the author's alone and do not n

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