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Panthers vs Bills Prediction, Odds, Spread, Over/Under & Betting Trends for NFL Week 15 Game on FanDuel Sportsbook

Devon Platana
Carolina Panthers vs Buffalo Bills prediction, odds, spread, over/under and betting trends for NFL Week 15 game.
Carolina Panthers vs Buffalo Bills prediction, odds, spread, over/under and betting trends for NFL Week 15 game. / Wesley Hitt/GettyImages
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Panthers vs Bills Week 15 Game Info

NFL Regular Season — Week 15 Game
Carolina Panthers (5-8, 3-3 Away) vs. Buffalo Bills (7-6, 3-3 Home)
Date: Sunday, December 19, 2021
Time: 1:00 p.m. EST
Venue: Highmark Stadium — Orchard Park, NY
Coverage: FOX

Panthers vs Bills Odds & Spread

All NFL regular betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: CAR: (+500) | BUF: (-700)
Spread: CAR: +14 (-110) | BUF: -14 (-110)
Total: 44 — Over: (-110) | Under: (-110)
Odds to Win Super Bowl LVI: CAR: (+1300) | BUF: (+10000)

Panthers vs Bills Prediction & Pick

All NFL predictions and picks are from numberFire's projection model.
Prediction: Buffalo Bills win (79.2%)

Panthers vs Bills Betting Trends

- Carolina is 2-8 straight up in its last 10 games.
- Buffalo is 4-2-1 against the spread (ATS) in its last seven games against Carolina.
- Carolina is 10-3 ATS in its last 13 road games.
- The total has hit the over in four of Buffalo's last six games played on Sunday.


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Devon Platana is not a FanDuel employee. The views expressed in his articles are the author's alone and do not necessarily reflect the views of FanDuel.

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