NFL Teams on Upset Alert in Week 5

After heavy favorites like the Los Angeles Rams and Indianapolis Colts stumbled in Week 4, NFL bettors are likely approaching Week 5 a little more cautiously.

If you're looking for some more potential upsets in Week 5, here are three NFL favorites that could lose this weekend.

*All NFL odds available via FanDuel Sportsbook.

3. Jacksonville Jaguars vs. Carolina Panthers (-3.5)

The clash between the Jacksonville Jaguars and Carolina Panthers features a battle between two unheralded QBs who have gone on to become national stories. Sixth-round rookie Gardner Minshew is 2-1 in his first three starts, while second-year QB Kyle Allen is undefeated through two starts in 2018. Carolina's rush defense has left something to be desired though, surrendering 130.8 yards per game on the ground, which is the ninth-worst mark in the NFL. That could be problem against Leonard Fournette, who just ran for 225 yards in Week 4 against Denver. Minshew has yet to throw an interception as a starter, and if he can maintain possession, Jacksonville can pound the rock and rely on its defense to earn this victory on the road.

2. Green Bay Packers vs. Dallas Cowboys (-3.5)

In Week 4, the Dallas Cowboys' offense didn't look like the explosive unit we saw over the first three games of the season. With Michael Gallup likely to remain on the sidelines here, Dallas could see a similar result against the Green Bay Packers. Green Bay has held opponents to 17.3 points per game (PPG), which is the seventh-best mark in football, and the Packers are surrendering 188.0 passing yards per game, which is the third-best total in the NFL. Aaron Rodgers is 6-1 in his last seven starts against Dallas, dating back to 2009, and he's 2-1 in his three career starts against Dak Prescott.

1. Cleveland Browns vs. San Francisco 49ers (-3.5)

It may have taken until Week 4, but it looks like the Cleveland Browns' much-hyped offense is finally humming. While the San Francisco 49ers are undefeated to start the season, they have yet to play a particularly impressive team, but have already developed some troubling habits. San Francisco has seen 22.2 percent of its drives end in a turnover, which is tied for the worst mark in the NFL with the New York Giants. Meanwhile, the Browns' defense has already forced eight takeaways, which is tied for the eighth-best mark in the NFL. If San Francisco continues to turn the ball over at this rate, Cleveland's explosive offense is more than capable of capitalizing, which could give the Browns an edge.

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Max Staley is not a FanDuel employee. In addition to providing DFS gameplay advice, Max Staley also participates in DFS contests on FanDuel using his personal account, username mstaley1212. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.