Louisville vs Wake Forest Point Spread, Over/Under, Moneyline and Betting Trends for College Football Week 5 Game

Larry Rupp
Louisville Cardinals vs Wake Forest Demon Deacons prediction, odds, spread, over/under and betting trends for college football Week 5 game.
Louisville Cardinals vs Wake Forest Demon Deacons prediction, odds, spread, over/under and betting trends for college football Week 5 game. / Ryan M. Kelly/Getty Images
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Week 5's slate of NCAA college football games includes a showdown between the Louisville Cardinals and No. 24 Wake Forest Demon Deacons.

Here's everything you need to know before placing your bet for this game on FanDuel Sportsbook.

Louisville vs Wake Forest Point Spread

The Demon Deacons are 7.5-point home favorites against the Cardinals. Wake Forest is -104 to cover the spread, while Louisville is -115 to cover as the 7.5-point underdog.

Louisville vs Wake Forest Over/Under

The over/under for the Louisville vs Wake Forest Week 5 college football matchup is set at 62.5, with -112 odds on the over and -108 odds on the under.

Louisville vs Wake Forest Moneyline

The Cardinals vs Demon Deacons moneyline has Wake Forest as a -290 favorite, while Louisville is the +225 underdog on the road.

Louisville vs Wake Forest Betting Trends

- Louisville is 6-2 in eight all-time head-to-head matchups against Wake Forest.
- Louisville defeated Wake Forest, 45-21, in their last meeting on Dec. 12, 2020.
- Louisville is 1-6 straight up in its last seven road games.
- Wake Forest is 6-0 straight up in its last six home games.
- The total has hit the over in 13 of Louisville's last 20 games.
- The total has hit the over in four of Wake Forest's last five games against Louisville.

Louisville vs Wake Forest Odds

All NCAAF betting lines, odds and prop bets are available on FanDuel Sportsbook.
Moneyline: LOU: (+225) | WFU: (-290)
Spread: LOU: +7.5 (-115) | WFU: -7.5 (-104)
Total: 62.5 – Over: (-112) | Under: (-108)
Public (Spread) Betting Percentages via oddsFireLOU: (N/A) | WFU: (N/A)


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Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

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