Giants vs Yankees Prediction, Odds & Best Bet for April 2 (Jhony Brito Earns Win in MLB Debut)

San Francisco Giants vs New York Yankees prediction, odds and betting insights for MLB regular season game.
San Francisco Giants vs New York Yankees prediction, odds and betting insights for MLB regular season game. / AP Photos/Seth Wenig

Giants vs. Yankees Game Info

  • Date: Sunday, April 2, 2023
  • Time: 1:35 p.m. ET
  • Venue: Yankee Stadium -- Bronx, NY
  • Coverage: YES and NBCS BA

The 2023 MLB season continues on Sunday with an exciting showdown between the San Francisco Giants and New York Yankees. The teams have split the first two games of the opening series, with the Yankees emerging victorious 5-0 on Thursday and the Giants earning a 7-5 win on Saturday.

The Giants will aim to pull off an upset with Ross Stripling on the mound as he is set to make his San Francisco debut. Meanwhile, Jhony Brito is making his major league debut as the Yankees' starter (3.71 ERA in minors). Which team will give the fans something to cheer about?

Giants vs. Yankees Odds & Spread

  • All MLB betting lines, odds and prop bets are from FanDuel Sportsbook.
  • Moneyline: SF: (+126) | NYY: (-148)
  • Spread: SF: +1.5 (-164) | NYY: -1.5 (+136)
  • Total: 8.5 -- Over: (-102) | Under: (-120)

The Yankees enter this interleague matchup as home favorites on the moneyline at FanDuel Sportsbook. This game also has a projected total of 8.5 runs, which the under favored at -120 odds.

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Giants vs. Yankees Betting Trends

  • San Francisco is 1-5 straight up in its last six games against the Yankees.
  • The total has hit the under in eight of San Francisco's last 10 games.
  • The Yankees are 12-6 straight up in their last 18 home games.
  • The total has hit the over in four of the Yankees' last five games against San Francisco.

Giants vs. Yankees Prediction & Pick

Both of these pitchers enter the 2023 season with momentum. Stripling is coming off a career year in Toronto as he posted a 10-4 record to go along with a 3.01 ERA and 1.02 WHIP (32 appearances). On the other side, Brito logged a 2.08 ERA and 0.92 WHIP in four Spring Training outings (13.2 innings).

The major difference in this game is that these Yankees hitters have seen Stripling a lot before. DJ LeMahieu is 10-for-26 (.385) in his career against Stripling, while Giancarlo Stanton has homered off the veteran. Stripling posted a subpar 4.70 ERA in two starts against the Yankees in the 2022 season.

Of course, none of the San Francisco hitters have seen what Brito brings to the table. The 25-year-old regularly pounds the strike zone, which will come in handy against a lineup that strikes out more than the MLB average. He has a shot to confuse hitters in the early going with a nasty arsenal of pitches.

Final Score Prediction: Giants: 3 | Yankees: 5

Giants vs. Yankees Best Bet

This game has low-scoring battle written all over it. Stripling excels at keeping the ball in the yard, which means the Yankees are going to have to string together multiple hits to score. Even if Brito struggles, New York can rely on a bullpen that finished the 2022 season with a 2.97 ERA (No. 3 in MLB). The total has hit the under in 10 of the Yankees' last 11 home games against San Francisco.

Bet: Under 8.5 Total Runs (-120)

Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

Game odds refresh periodically and are subject to change.