Week 6 is the first time four teams are on bye, with the Buffalo Bills, Chicago Bears, Indianapolis Colts and Oakland Raiders all off. This alone can create headaches when setting fantasy lineups and injuries complicate things even more.
There are plenty of injury updates worth tracking each and every week and with Davante Adams already ruled out for the Green Bay Packers, here are a few other fantasy football situations worth monitoring leading up to kickoff on Sunday.
1. Davante Adams Injury Opens Up Targets for Marquez Valdes-Scantling and Geronimo Allison
As mentioned above, Adams was ruled out for the second week in a row with a toe injury. His absence will open up more targets for the rest of the Packers' receiving corps, specifically Marquez Valdes-Scantling, Geronimo Allison and Jimmy Graham. While the Packers didn't need to throw much last week, with Aaron Jones taking over the game, a divisional matchup with the Detroit Lions on Monday night could see lots of points and thus a more active passing game. Adams' injury gives MVS and Allison the biggest upgrades in the Green Bay offense for Week 6 fantasy football.
2. Alvin Kamara Injury Update Could Boost Latavius Murray's Fantasy Value
After being a mid-week addition to the injury report, Alvin Kamara ended the week as a DNP, clouding his Week 6 status. If Kamara sits, Latavius Murray becomes a virtual must-start option in what would likely be a workhorse role, facing a Jacksonville Jaguars defense that has given up the eighth-most PPR fantasy points per game to opposing running backs.
3. David Johnson Injury Could Lead to Increased Role for Chase Edmonds
After missing practice earlier in the week, David Johnson's Week 6 status was seemingly in doubt. While he was able to practice in a limited fashion on Friday, Cardinals head coach Kliff Kingsbury won't guarantee if his lead back will play against the Atlanta Falcons this weekend. If Johnson misses, Chase Edmonds becomes a must-start in a fantasy-friendly matchup with the Falcons.
4. Malcolm Brown and Darrell Henderson in Line for Larger Roles With Todd Gurley Out
After failing to log any practice reps this week, it appears that Todd Gurley will miss Week 6, positioning Malcolm Brown and Darrell Henderson for larger roles in the Rams' offense. Brown is expected to be the team's lead back, giving him RB2 upside against the San Francisco 49ers. While the Henderson hasn't played an offensive snap since Week 1, head coach Sean McVay mentioned that this could be the week the team needs to rely on the rookie. Both backs would be fantasy relevant, if Gurley does ultimately sit out in Week 6.
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