Colts vs 49ers Point Spread, Over/Under, Moneyline and Betting Trends for NFL Week 7 Sunday Night Football

Week 7's slate of games includes a showdown between the Indianapolis Colts and San Francisco 49ers.

Here's everything you need to know before placing your bet for this game on FanDuel Sportsbook.

Colts vs 49ers Point Spread

The 49ers are 4.5-point home favorites against the Colts. San Francisco is -105 to cover the spread, while Indianapolis is -115 to cover as a 4.5-point underdog.

Colts vs 49ers Over/Under

The over/under for the Colts vs 49ers Week 7 NFL matchup is set at 42.5, with -114 odds on the over and -106 odds on the under.

Colts vs 49ers Moneyline

The Colts vs 49ers moneyline has San Francisco as a -210 favorite, while Indianapolis is a +176 underdog on the road.

Colts vs 49ers Betting Trends

- Indianapolis 4-1 against the spread (ATS) in its last five games.
- San Francisco is 1-4 ATS in its last five games this season.
- The total has hit the over in five of Indianapolis' last six road games.
- The total has hit the over in five of San Francisco's last six games against AFC South opponents.

Colts vs 49ers Odds & Spread

All NFL regular betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: IND: (+176) | SF: (-210)
Spread: IND: +4.5 (-115) | SF: -4.5 (-105)
Total: 42.5 — Over: (-114) | Under: (-106)
Public (Spread) Betting Percentages via oddsFire: IND: (N/A) | SF: (N/A)
Odds to Win Super Bowl LVI: IND: (+10000) | SF: (+4500)

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Devon Platana is not a FanDuel employee. The views expressed in his articles are the author's alone and do not necessarily reflect the views of FanDuel.