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Bills vs Patriots Point Spread, Over/Under, Moneyline and Betting Trends for NFL Week 16 Monday Night Football

Zach Brunner
Bills vs Patriots point spread, over/under, moneyline and betting trends for Week 16.
Bills vs Patriots point spread, over/under, moneyline and betting trends for Week 16. / Mark Brown/Getty Images
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The Buffalo Bills hit the road to face the New England Patriots at Gillette Stadium in Week 16 NFL action on Sunday.

Here's everything you need to know before placing your bet for this game on FanDuel Sportsbook.

Bills vs Patriots Point Spread

The Bills are 7-point road favorites in this matchup. The Patriots are 7-point home underdogs, with -112 odds to cover the spread. Buffalo has -108 odds to cover.

Bills vs Patriots Over/Under

The over/under for the Bills vs Patriots Week 16 NFL matchup is set at 46 total points, with -110 odds on both the over and the under.

Bills vs Patriots Moneyline

The Bills vs Patriots moneyline has Buffalo as -330 road favorites, while New England is the +265 underdog at home.

Bills vs Patriots Betting Trends

- Buffalo is 5-0 against the spread (ATS) in its last five games.
- Buffalo is 7-1 straight up in its last eight games.
- The total has hit the under in each of the last five games for New England.
- New England is 17-2 straight up in its last 19 home games against Buffalo.

Bills vs Patriots Odds

All NFL betting lines, odds, and prop bets are available on FanDuel Sportsbook.
Moneyline: BUF: (-330) | NE: (+265)
Spread: BUF: -7 (-108) | NE: +7 (-112)
Total: 46 – Over: (-110) | Under: (-110)
Public (Spread) Betting Percentages via oddsFire: BUF: (96%) | NE: (4%)
Odds to Win Super Bowl LV: BUF: (+1000) | NE: (N/A)


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