Bills vs Cardinals Predictions and Expert Picks for Week 10 NFL Game

Larry Rupp
Buffalo Bills vs Arizona Cardinals predictions and expert picks for Week 10 NFL game.
Buffalo Bills vs Arizona Cardinals predictions and expert picks for Week 10 NFL game. / Timothy T Ludwig/Getty Images

Two teams with their eyes set on making the NFL Playoffs meet up in Week 10 as Kyler Murray and the Arizona Cardinals (5-3) host Josh Allen and the Buffalo Bills (7-2). The Bills are looking to win their fourth consecutive game, but are 2-point road underdogs in this one, according to FanDuel Sportsbook's NFL betting odds.

Let's see what the experts are predicting to happen in this Week 10 Bills-Cardinals showdown.

Bills vs Cardinals Picks Week 10

CBS Sports picks are from their panel of experts, numberFire picks are from their NFL game projections, Sporting News picks are from Vinnie Iyer, and betting favorites are from FanDuel Sportsbook's Week 10 NFL odds.

CBS Sports: Cardinals (2), Bills (2)
numberFire: Cardinals
Sporting News: Bills
Betting Favorite: Cardinals -2

Against the Spread:
CBS Sports: Cardinals (2), Bills (2)
Sporting News: Bills

As expected, the experts are pretty split on who they predict will win and cover the spread in one of the most highly anticipated matchups on the Week 10 schedule.

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Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.