NFL - Odds & Predictions

49ers' Super Bowl Odds Make Surprising Shift After Trey Lance Injury

Isaiah De Los Santos
The San Francisco 49ers' Super Bowl LVII odds have made a surprising shift after Trey Lance's season-ending injury.
The San Francisco 49ers' Super Bowl LVII odds have made a surprising shift after Trey Lance's season-ending injury. / (AP Photo/Tony Avelar)

The San Francisco 49ers were dealt a huge blow on Sunday after starting quarterback Trey Lance exited with what's now been deemed a season-ending ankle injury. However, San Francisco is one of the teams best equipped to survive an injury at QB thanks to Jimmy Garoppolo's return this offseason, and he went on to lead the 49ers to victory against the Seattle Seahawks in Lance's absence.

With Lance now out for the rest of 2022 and Garoppolo taking his place, San Francisco's Super Bowl odds on FanDuel Sportsbook have taken a surprising turn.

Trey Lance Injury Update

San Francisco 49ers Super Bowl Odds

The 49ers entered Week 2 with +2200 odds to win Super Bowl LVII. That number has actually improved to +1800 now, despite Lance's injury.

Losing your starting quarterback is usually a death sentence for most championship contenders, but it appears oddsmakers are bullish on Garoppolo taking over under center once again. History is certainly on his side considering his 31-14 regular-season record as a starter with the 49ers, not to mention a Super Bowl appearance and two NFC Conference Championship appearances on his resume.

Garoppolo looked solid as usual in relief of Lance on Sunday, completing 13 of 21 passes for 154 yards and 1 touchdown against the Seattle Seahawks. He also rushed for 5 yards, including a 1-yard TD score in the fourth quarter.

49ers vs Broncos Week 3 Odds

The veteran signal-caller will now get a full week to prepare for a Sunday Night Football matchup against the Denver Broncos. The 49ers head into that clash as 1-point road favorites according to FanDuel Sportsbook's NFL odds.

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Isaiah De Los Santos is not a FanDuel employee. In addition to providing DFS gameplay advice, Isaiah De Los Santos also participates in DFS contests on FanDuel using his personal account, username zayyy05328. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.