49ers vs Lions Predictions and Expert Picks for Week 1 NFL Game From FanDuel Sportsbook

Devon Platana
San Francisco 49ers vs Detroit Lions predictions and expert picks for Week 1 NFL Game.
San Francisco 49ers vs Detroit Lions predictions and expert picks for Week 1 NFL Game. / Norm Hall/Getty Images
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Today's slate of NFL games includes a clash between the San Francisco 49ers and Detroit Lions.

49ers vs Lions Prediction and Pick Today

ESPN picks are from their Football Power Index (FPI) matchup predictor, numberFire picks are from their analytics projection models, FiveThirtyEight picks are from their NFL projections and betting favorites are according to FanDuel Sportsbook's 49ers-Lions betting odds and lines.

NFL Picks Straight Up

ESPN: 49ers
numberFire: 49ers
FiveThirtyEight: 49ers
Betting Favorite: 49ers (-7.5)

Lions vs 49ers Prediction

Winner: 49ers (4)


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Devon Platana is not a FanDuel employee. The views expressed in his articles are the author's alone and do not necessarily reflect the views of FanDuel.

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