Week 11 NFL Odds and Lines Have 49ers Facing Largest Spread and Chiefs vs Chargers as Highest Total

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Week 11 in the NFL season features a 14-game slate that boasts some pretty heavy favorites, like the San Francisco 49ers and Minnesota Vikings, according to FanDuel Sportsbook.

NFL Point Spreads

Looking at the totals for Week 11, the game with the highest over/under belongs to the AFC West matchup between the Kansas City Chiefs and Los Angeles Chargers on "Monday Night Football." The total for this game is set at 53, and the last two matchups between these two have seen a combined average of 61.5 points.

On the other end, the matchup between the New York Jets and Washington Redskins has the lowest over/under of the week, with a total set at 37.5. This is one of only three games with an over/under set at fewer than 40 points.

The largest spread of the week, meanwhile, comes in a battle between two teams in the NFC West, with the San Francisco 49ers being favored by 13.5 points at home over the Arizona Cardinals. This is a rematch of the Week 9 game, which the 49ers won, 28-25.

The smallest spread, however, is the same as the lowest over/under, with the Redskins being 1-point favorites at home over the Jets.

There's still plenty of time for injuries or other developments to shift these odds, so bettors would be wise to closely monitor the spreads as the week progresses.

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