Week 10 Fantasy Picks: Start 'Em, Sit 'Em for Buffalo Bills vs Arizona Cardinals

Max Staley
Josh Allen fantasy outlook makes him a great start against the Arizona Cardinals.
Josh Allen fantasy outlook makes him a great start against the Arizona Cardinals. / Timothy T Ludwig/Getty Images

The Week 10 slate is loaded, but the matchup between the Buffalo Bills and Arizona Cardinals might be the most exciting game of the week. In fact, FanDuel Sportsbook's Week 10 NFL odds give this game the highest over/under total of the week, at 56.

If you need some help with your fantasy lineups, here's some start 'em, sit 'em advice for this Week 10 showdown.

Who Should I Start Fantasy Football

Start Josh Allen, QB, Buffalo Bills: Josh Allen broke out of his mini slump in a big way last week. The legitimate MVP candidate put up 415 passing yards and 4 total touchdowns while completing 31-of-38 passes against the Seattle Seahawks. Arizona's defense will be a much tougher test, with the Cardinals sitting at No. 10 in DVOA, but that's not enough to justify benching fantasy's QB4.

Start Christian Kirk, WR, Arizona Cardinals: Christian Kirk is on fire right now. From Week 5-9, Kirk has put up a total of 79.4 PPR points, making him fantasy's overall WR11 during that span. The Bills aren't exactly an imposing defense (No. 15 in DVOA), and this one is likely to be a shootout, so Kirk should have little trouble keeping the momentum going here.

Sit Devin Singletary, RB, Buffalo Bills: Though the Buffalo Bills offense still appears as explosive as ever, this backfield is looking like one to avoid for fantasy purposes. Devin Singletary is ceding red zone touches to Zack Moss, essentially erasing Singletary's TD upside. To make matters worse, he's only averaging 11.0 opportunities (8.0 carries plus 3.0 targets) per game over his last three outings. With little hope of finding the end zone (1 TD in 2020) and a limited workload, Singletary is not someone you want facing a top-10 defense by DVOA.

Sit Chase Edmonds, RB, Seattle Seahawks: Chase Edmonds was one of the most popular waiver wire pickups of the week once Kenyan Drake went down. But in his first real action as a starter, he sure didn't showcase much of that RB1 potential we thought he had. Edmonds turned 28 opportunities into 88 yards from scrimmage, and that's just not the kind of efficiency he needed to post in order to run away with this job. With Drake potentially returning this week, Edmonds' value is trending in the wrong direction.

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Max Staley is not a FanDuel employee. In addition to providing DFS gameplay advice, Max Staley also participates in DFS contests on FanDuel using his personal account, username mstaley1212. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.