Packers vs 49ers Prediction, Odds, Spread, Over/Under & Betting Trends for NFL Week 3 Sunday Night Football Game

Max Staley
Green Bay Packers vs San Francisco 49ers prediction, odds, spread and over/under for NFL Week 3.
Green Bay Packers vs San Francisco 49ers prediction, odds, spread and over/under for NFL Week 3. / Sean M. Haffey/Getty Images
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Packers vs 49ers Week 3 Game Info

NFL Regular Season — Week 3 Sunday Night Football Game
Green Bay Packers (1-1, 0-1 Away) vs. San Francisco 49ers (2-0, 0-0 Home)
Date: Sunday, September 26, 2021
Time: 8:25 p.m. EST
Venue: Levi's Stadium – Santa Clara, CA
Coverage: NBC

Packers vs 49ers Odds & Spread

All NFL regular betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: GB: (+136) | SF: (-162)
Spread: GB: +3 (-110) | SF: -3 (-110)
Total: 50.5 — Over: (-110) | Under: (-110)
Public (Spread) Betting Percentages via oddsFire: GB: (N/A) | SF: (N/A)
Odds to Win Super Bowl LVI: GB: (+1500) | SF: (+1300)

Packers vs 49ers Prediction & Pick

All NFL predictions and picks are from numberFire's projection model and will be updated when available.
Prediction: 49ers win (54.5%)

Packers vs 49ers Betting Trends

- Green Bay is 1-1 against the spread (ATS) this season.
- The total has hit the over in one of Green Bay's two games this season.
- San Francisco is 1-1 ATS this season.
- The total has hit the over in one of San Francisco's two games this season.


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Max Staley is not a FanDuel employee. In addition to providing DFS gameplay advice, Max Staley also participates in DFS contests on FanDuel using his personal account, username mstaley1212. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.

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