Giants vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for May 22

The MLB schedule on Sunday includes the San Francisco Giants taking on the San Diego Padres.

All the info you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Giants vs Padres Game Info

• San Francisco Giants (22-17) vs. San Diego Padres (26-14)
• Date: Sunday, May 22, 2022
• Time: 4:05 PM ET
• Venue: Oracle Park -- San Francisco, California

Giants vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-142) | SD: (+120)
• Spread: SF: -1.5 (+146) | SD: +1.5 (-176)
• Total: 8 -- Over: (-104) | Under: (-118)

Giants vs Padres Probable Starting Pitchers

The San Francisco Giants will give the start to Alex Wood (3-2, 2.17 ERA) looking for win No. 4 on the season, and the Padres will counter with MacKenzie Gore (2-1, 2.17).

Giants vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (61.5%)

Giants vs Padres Moneyline

San Francisco is the favorite, -142 on the moneyline, while San Diego is a +120 underdog on the road.

Giants vs Padres Spread

The Padres are +1.5 on the spread (-176 to cover), and San Francisco is +146 to cover the runline.

Giants vs Padres Over/Under

Giants versus Padres, on May 22, has an over/under of 8, with the over being -104 and the under -118.

Giants vs Padres Betting Trends

• The Giants have come away with 18 wins in the 30 contests they have been listed as the favorites in this season.
• This season, San Francisco has come away with a win 10 times in 18 chances when named as a favorite of at least -142 or better on the moneyline.
• Contests with San Francisco have gone over the total set by sportsbooks in 20 of 36 chances this season.
• The Padres are 10-6 in games they were the underdog on the moneyline (winning 62.5% of those games).
• In games it has played as a moneyline underdog with odds of +120 or longer, San Diego has gone 3-2 (60%).
• San Diego has played in 38 games with a set over/under, and has combined with their opponents to go over the total 17 times (17-21-0).