Bill vs 49ers Point Spread, Over/Under, Moneyline and Betting Trends for NFL Week 13

Zach Brunner
Bill vs 49ers point spread, over/under, moneyline and betting trends for Week 13.
Bill vs 49ers point spread, over/under, moneyline and betting trends for Week 13. / Abbie Parr/Getty Images
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The Buffalo Bills hit the road to face the San Francisco 49ers at State Farm Stadium in Week 13 NFL action on Monday.

Here's everything you need to know before placing your bet for this game on FanDuel Sportsbook.

Bill vs 49ers Point Spread

The Bills are 1-point road underdogs. The 49ers are 1-point home favorites, with -110 odds on both to cover the spread.

Bill vs 49ers Over/Under

The over/under for the Bill vs 49ers Week 13 NFL matchup is set at 46.5 total points, with -115 odds on the over and -105 on the under.

Bill vs 49ers Moneyline

The Bill vs 49ers moneyline has Buffalo as -102 road underdogs, while San Francisco is the -116 favorite at home.

Bill vs 49ers Betting Trends

- Buffalo is 5-0 against the spread (ATS) in its last five games against an NFC opponent.
- The total has hit the over in eight of Buffalo's last 11 games.
- San Francisco is 1-4 ATS in its five home games this season.
- The total has hit the over in four of San Francisco's last six games against Buffalo.

Bill vs 49ers Odds

All betting lines, odds and prop bets are available on FanDuel Sportsbook.
Moneyline: BUF: (-102) | SF: (-116)
Spread: 
BUF: +1 (-110) | SF: -1 (-110)
Total: 46.5 – Over: (-115) | Under: (-105)
Public (Spread) Betting Percentages via oddsFire: BUF: (79%) | SF: (21%)
Odds to Win Super Bowl LV:
 BUF: (+2200) | SF: (+10000)


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