Best College Football Games Week 6: Predictions, Odds, Picks, Best Bets

Top-25 teams will take the field in 15 games on the Week 6 college football schedule. That includes the No. 3 Miami (FL) Hurricanes squaring off against the No. 18 Florida State Seminoles at Bobby Bowden Field at Doak Campbell Stadium.

There is college football action this week, and we have you covered with the betting odds you need to get an edge.

For additional insights, check out the latest college football betting picks from FanDuel Research's staff of writers.

BYU vs. West Virginia

• Matchup: West Virginia Mountaineers at No. 23 BYU Cougars
• Projected Favorite: BYU (85.53% win probability)
• Spread: BYU (-18.5)
• Total: 47.5
• Time: 10:30 p.m. ET
• Date: Oct. 3
• TV Channel: ESPN

Bet on BYU vs. West Virginia with FanDuel Sportsbook.

Georgia vs. Kentucky

• Matchup: Kentucky Wildcats at No. 12 Georgia Bulldogs
• Projected Favorite: Georgia (87.03% win probability)
• Spread: Georgia (-20.5)
• Total: 48.5
• Time: 12 p.m. ET
• Date: Oct. 4
• TV Channel: ABC

Bet on Georgia vs. Kentucky with FanDuel Sportsbook.

Purdue vs. Illinois

• Matchup: No. 22 Illinois Fighting Illini at Purdue Boilermakers
• Projected Favorite: Illinois (78.88% win probability)
• Spread: Illinois (-9.5)
• Total: 55.5
• Time: 12 p.m. ET
• Date: Oct. 4
• TV Channel: BTN

Bet on Purdue vs. Illinois with FanDuel Sportsbook.

Michigan vs. Wisconsin

• Matchup: Wisconsin Badgers at No. 20 Michigan Wolverines
• Projected Favorite: Michigan (86.30% win probability)
• Spread: Michigan (-16.5)
• Total: 43.5
• Time: 12 p.m. ET
• Date: Oct. 4
• TV Channel: FOX

Bet on Michigan vs. Wisconsin with FanDuel Sportsbook.

Cincinnati vs. Iowa State

• Matchup: No. 14 Iowa State Cyclones at Cincinnati Bearcats
• Projected Favorite: Iowa State (54.51% win probability)
• Spread: Cincinnati (-1.5)
• Total: 55.5
• Time: 12 p.m. ET
• Date: Oct. 4
• TV Channel: ESPN2

Bet on Cincinnati vs. Iowa State with FanDuel Sportsbook.

Louisville vs. Virginia

• Matchup: No. 24 Virginia Cavaliers at Louisville Cardinals
• Projected Favorite: Louisville (79.95% win probability)
• Spread: Louisville (-6.5)
• Total: 62.5
• Time: 3:30 p.m. ET
• Date: Oct. 4
• TV Channel: ESPN2

Bet on Louisville vs. Virginia with FanDuel Sportsbook.

Alabama vs. Vanderbilt

• Matchup: No. 16 Vanderbilt Commodores at No. 10 Alabama Crimson Tide
• Projected Favorite: Alabama (79.32% win probability)
• Spread: Alabama (-10.5)
• Total: 55.5
• Time: 3:30 p.m. ET
• Date: Oct. 4
• TV Channel: ABC

Bet on Alabama vs. Vanderbilt with FanDuel Sportsbook.

UCLA vs. Penn State

• Matchup: No. 7 Penn State Nittany Lions at UCLA Bruins
• Projected Favorite: Penn State (90.48% win probability)
• Spread: Penn State (-24.5)
• Total: 50.5
• Time: 3:30 p.m. ET
• Date: Oct. 4
• TV Channel: CBS

Bet on UCLA vs. Penn State with FanDuel Sportsbook.

Notre Dame vs. Boise State

• Matchup: Boise State Broncos at No. 21 Notre Dame Fighting Irish
• Projected Favorite: Notre Dame (77.27% win probability)
• Spread: Notre Dame (-20.5)
• Total: 62.5
• Time: 3:30 p.m. ET
• Date: Oct. 4
• TV Channel: NBC

Bet on Notre Dame vs. Boise State with FanDuel Sportsbook.

Florida vs. Texas

• Matchup: No. 9 Texas Longhorns at Florida Gators
• Projected Favorite: Texas (62.74% win probability)
• Spread: Texas (-6.5)
• Total: 41.5
• Time: 3:30 p.m. ET
• Date: Oct. 4
• TV Channel: ESPN

Bet on Florida vs. Texas with FanDuel Sportsbook.

Oklahoma vs. Kent State

• Matchup: Kent State Golden Flashes at No. 5 Oklahoma Sooners
• Projected Favorite: Oklahoma (97.13% win probability)
• Spread: Oklahoma (-45.5)
• Total: 53.5
• Time: 4 p.m. ET
• Date: Oct. 4
• TV Channel: SEC Network

Bet on Oklahoma vs. Kent State with FanDuel Sportsbook.

Houston vs. Texas Tech

• Matchup: No. 11 Texas Tech Red Raiders at Houston Cougars
• Projected Favorite: Texas Tech (70.70% win probability)
• Spread: Texas Tech (-10.5)
• Total: 51.5
• Time: 7 p.m. ET
• Date: Oct. 4
• TV Channel: ESPN

Bet on Houston vs. Texas Tech with FanDuel Sportsbook.

Florida State vs. Miami (FL)

• Matchup: No. 3 Miami (FL) Hurricanes at No. 18 Florida State Seminoles
• Projected Favorite: Miami (FL) (77.20% win probability)
• Spread: Miami (FL) (-4.5)
• Total: 53.5
• Time: 7:30 p.m. ET
• Date: Oct. 4
• TV Channel: ABC

Bet on Florida State vs. Miami (FL) with FanDuel Sportsbook.

Texas A&M vs. Mississippi State

• Matchup: Mississippi State Bulldogs at No. 6 Texas A&M Aggies
• Projected Favorite: Texas A&M (80.04% win probability)
• Spread: Texas A&M (-14.5)
• Total: 55.5
• Time: 7:30 p.m. ET
• Date: Oct. 4
• TV Channel: SEC Network

Bet on Texas A&M vs. Mississippi State with FanDuel Sportsbook.

Ohio State vs. Minnesota

• Matchup: Minnesota Golden Gophers at No. 1 Ohio State Buckeyes
• Projected Favorite: Ohio State (87.40% win probability)
• Spread: Ohio State (-23.5)
• Total: 44.5
• Time: 7:30 p.m. ET
• Date: Oct. 4
• TV Channel: NBC

Bet on Ohio State vs. Minnesota with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!