Michigan vs Wisconsin Prediction, Odds, Picks, Best Bets for Week 6 2025

The Michigan Wolverines will face the Wisconsin Badgers in college football action on Saturday.

We've got you covered, in terms of the vital information about NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

Michigan vs Wisconsin Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Michigan: (-1053) | Wisconsin: (+660)
• Spread: Michigan: -16.5 (-124) | Wisconsin: +16.5 (102)
• Total: 43.5 -- Over: (-110) | Under: (-110)

Michigan vs Wisconsin Betting Trends

• Michigan has two wins against the spread this year.
• Michigan owns one win ATS (1-1) as a 16.5-point favorite or greater this season.
• There have been three Michigan games (of four) that hit the over this season.
• Wisconsin has but one win versus the spread this season.
• Wisconsin is winless ATS (0-1) when playing as at least 16.5-point underdogs this season.
• A pair of Wisconsin four games in 2025 have gone over the point total.

Michigan vs Wisconsin Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Wolverines win (86.3%)

Michigan vs Wisconsin Point Spread

Wisconsin is the underdog by 16.5 points against Michigan. Wisconsin is -124 to cover the spread, and Michigan is +102.

Michigan vs Wisconsin Over/Under

A total of 43.5 points has been set for the Michigan-Wisconsin matchup on Oct. 4, with the over available at -110 and the under at -110.

Michigan vs Wisconsin Moneyline

Wisconsin is the underdog, +660 on the moneyline, while Michigan is a -1053 favorite.

Michigan vs. Wisconsin Points Insights

Michigan vs. Wisconsin Game Info

• Game day: Saturday, October 4, 2025
• Game time: 12 p.m. ET
• TV channel: FOX
• Location: Ann Arbor, Michigan
• Stadium: Michigan Stadium

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Check out even more in-depth Michigan vs. Wisconsin analysis on FanDuel Research.