Michigan vs Wisconsin Prediction, Odds, Picks, Best Bets for Week 6 2025

Saturday's slate in college football includes a matchup between the Michigan Wolverines and the Wisconsin Badgers.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the vital info regarding today's NCAA football betting odds.

Michigan vs Wisconsin Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Michigan: (-1000) | Wisconsin: (+660)
• Spread: Michigan: -17.5 (-106) | Wisconsin: +17.5 (-114)
• Total: 43.5 -- Over: (-110) | Under: (-110)

Michigan vs Wisconsin Betting Trends

• Michigan has two wins against the spread this season.
• As a 17.5-point or greater favorite, Michigan has one win ATS (1-1) this season.
• Michigan has played four games this year, and three of them have hit the over.
• Wisconsin has but one win versus the spread this season.
• Wisconsin is winless ATS (0-1) when playing as at least 17.5-point underdogs this year.
• Two Wisconsin games (of four) have gone over the point total this season.

Michigan vs Wisconsin Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Wolverines win (87.2%)

Michigan vs Wisconsin Point Spread

Wisconsin is a 17.5-point underdog against Michigan. Wisconsin is -114 to cover the spread, and Michigan is -106.

Michigan vs Wisconsin Over/Under

A combined point total of 43.5 has been set for Michigan-Wisconsin on Oct. 4, with the over at -110 and the under at -110.

Michigan vs Wisconsin Moneyline

Wisconsin is the underdog, +660 on the moneyline, while Michigan is a -1000 favorite.

Michigan vs. Wisconsin Points Insights

Michigan vs. Wisconsin Game Info

• Game day: Saturday, October 4, 2025
• Game time: 12 p.m. ET
• TV channel: FOX
• Location: Ann Arbor, Michigan
• Stadium: Michigan Stadium

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Check out even more in-depth Michigan vs. Wisconsin analysis on FanDuel Research.