Ohio State vs Minnesota Prediction, Odds, Picks, Best Bets for Week 6 2025

The Ohio State Buckeyes are among the college football teams playing on Saturday, versus the Minnesota Golden Gophers.

Get the latest NCAA football odds ahead of this game on FanDuel Sportsbook.

Ohio State vs Minnesota Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Ohio State: (-3448) | Minnesota: (+1280)
• Spread: Ohio State: -23.5 (-110) | Minnesota: +23.5 (-110)
• Total: 44.5 -- Over: (-105) | Under: (-115)

Ohio State vs Minnesota Betting Trends

• Against the spread, Ohio State is 3-1-0 this season.
• Ohio State owns one win ATS (1-1) as a 23.5-point favorite or greater this season.
• Ohio State has had one game (of four) go over the total this year.
• Minnesota has one win against the spread this season.
• Two Minnesota games (of four) have hit the over this year.

Ohio State vs Minnesota Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Buckeyes win (87.4%)

Ohio State vs Minnesota Point Spread

Minnesota is the underdog by 23.5 points against Ohio State. Minnesota is -110 to cover the spread, and Ohio State is -110.

Ohio State vs Minnesota Over/Under

Ohio State versus Minnesota, on Oct. 4, has an over/under of 44.5, with the over being -105 and the under -115.

Ohio State vs Minnesota Moneyline

The Ohio State vs Minnesota moneyline has Ohio State as a -3448 favorite, while Minnesota is a +1280 underdog.

Ohio State vs. Minnesota Points Insights

Ohio State vs. Minnesota Game Info

• Game day: Saturday, October 4, 2025
• Game time: 7:30 p.m. ET
• TV channel: NBC
• Location: Columbus, Ohio
• Stadium: Ohio Stadium

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Check out even more in-depth Ohio State vs. Minnesota analysis on FanDuel Research.