Ohio State vs Minnesota Prediction, Odds, Picks, Best Bets for Week 6 2025

Saturday's slate in college football includes a matchup between the Ohio State Buckeyes and the Minnesota Golden Gophers.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

Ohio State vs Minnesota Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Ohio State: (-4000) | Minnesota: (+1500)
• Spread: Ohio State: -23.5 (-110) | Minnesota: +23.5 (-110)
• Total: 42.5 -- Over: (-110) | Under: (-110)

Ohio State vs Minnesota Betting Trends

• Against the spread, Ohio State is 3-1-0 this year.
• As a 23.5-point or greater favorite, Ohio State has one win ATS (1-1) this season.
• Ohio State has had one game (of four) go over the total this season.
• Minnesota has but one win versus the spread this year.
• Minnesota has played two games (out of four) which finished over the total this year.

Ohio State vs Minnesota Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Buckeyes win (87.2%)

Ohio State vs Minnesota Point Spread

Minnesota is a 23.5-point underdog against Ohio State. Minnesota is -110 to cover the spread, and Ohio State is -110.

Ohio State vs Minnesota Over/Under

A total of 42.5 points has been set for the Ohio State-Minnesota game on Oct. 4, with the over available at -110 and the under at -110.

Ohio State vs Minnesota Moneyline

The Ohio State vs Minnesota moneyline has Ohio State as a -4000 favorite, while Minnesota is a +1500 underdog.

Ohio State vs. Minnesota Points Insights

Ohio State vs. Minnesota Game Info

• Game day: Saturday, October 4, 2025
• Game time: 7:30 p.m. ET
• TV channel: NBC
• Location: Columbus, Ohio
• Stadium: Ohio Stadium

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Check out even more in-depth Ohio State vs. Minnesota analysis on FanDuel Research.