Penn State vs UCLA Prediction, Odds, Picks, Best Bets for Week 6 2025

The Saturday schedule in college football includes a matchup between the Penn State Nittany Lions and the UCLA Bruins.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the most important info about today's NCAA football betting odds.

Penn State vs UCLA Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Penn State: (-4000) | UCLA: (+1500)
• Spread: Penn State: -24.5 (-110) | UCLA: +24.5 (-110)
• Total: 48.5 -- Over: (-114) | Under: (-106)

Penn State vs UCLA Betting Trends

• Penn State is winless against the spread this season.
• Penn State has yet to win ATS (0-3) when playing as at least 24.5-point favorites this season.
• This season, three of Penn State's four games have gone over the point total.
• UCLA has posted one win against the spread this season.
• One UCLA game (out of four) has hit the over this season.

Penn State vs UCLA Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Nittany Lions win (90.6%)

Penn State vs UCLA Point Spread

UCLA is an underdog by 24.5 points versus Penn State. UCLA is -110 to cover the spread, and Penn State is -110.

Penn State vs UCLA Over/Under

The Penn State-UCLA game on Oct. 4 has been given an over/under of 48.5 points. The over is -114 and the under is -106.

Penn State vs UCLA Moneyline

Penn State is the favorite, -4000 on the moneyline, while UCLA is a +1500 underdog.

Penn State vs. UCLA Points Insights

Penn State vs. UCLA Game Info

• Game day: Saturday, October 4, 2025
• Game time: 3:30 p.m. ET
• TV channel: CBS
• Location: Pasadena, California
• Stadium: Rose Bowl

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