Notre Dame vs Boise State Prediction, Odds, Picks, Best Bets for Week 6 2025

College football's Saturday slate includes the Notre Dame Fighting Irish taking on the Boise State Broncos.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA football odds and spreads you need to know.

Notre Dame vs Boise State Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Notre Dame: (-1786) | Boise State: (+980)
• Spread: Notre Dame: -21.5 (-110) | Boise State: +21.5 (-110)
• Total: 62.5 -- Over: (-112) | Under: (-108)

Notre Dame vs Boise State Betting Trends

• Notre Dame has two wins against the spread this year.
• Notre Dame is unbeaten ATS (1-0) as a 21.5-point favorite or greater this season.
• Notre Dame and its opponent have not failed to hit the over in any game this season.
• Boise State has covered the spread three times in four games.
• Boise State has played four games this year, and three of them have gone over the total.

Notre Dame vs Boise State Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Fighting Irish win (81.7%)

Notre Dame vs Boise State Point Spread

Notre Dame is a 21.5-point favorite against Boise State. Notre Dame is -110 to cover the spread, and Boise State is -110.

Notre Dame vs Boise State Over/Under

Notre Dame versus Boise State, on Oct. 4, has an over/under of 62.5, with the over being -112 and the under -108.

Notre Dame vs Boise State Moneyline

Notre Dame is the favorite, -1786 on the moneyline, while Boise State is a +980 underdog.

Notre Dame vs. Boise State Points Insights

Notre Dame vs. Boise State Game Info

• Game day: Saturday, October 4, 2025
• Game time: 3:30 p.m. ET
• TV channel: NBC
• Location: South Bend, Indiana
• Stadium: Notre Dame Stadium

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Check out even more in-depth Notre Dame vs. Boise State analysis on FanDuel Research.