Virginia vs Louisville Point Spread, Over/Under, Moneyline and Betting Trends for College Football Week 6 Game

Week 6's slate of NCAA college football games includes a showdown between the Virginia Cavaliers and Louisville Cardinals.

Here's everything you need to know before placing your bet for this game on FanDuel Sportsbook.

Virginia vs Louisville Point Spread

The Cardinals are 2.5-point home favorites against the Cavaliers. Louisville is -108 to cover the spread, while Virginia is -112 to cover as the 2.5-point underdog.

Virginia vs Louisville Over/Under

The over/under for the Virginia vs Louisville Week 6 college football matchup is set at 69.5, with -104 odds on the over and -118 odds on the under.

Virginia vs Louisville Moneyline

The Cavaliers vs Cardinals moneyline has Louisville as a -140 favorite, while Virginia is the +114 underdog on the road.

Virginia vs Louisville Betting Trends

- Louisville is 5-4 in nine all-time head-to-head matchups against Virginia.
- Virginia defeated Louisville, 31-17, in their last meeting on Nov. 14, 2020.
- Virginia is 8-3 against the spread (ATS) in its last 11 games.
- Louisville is 2-5 ATS in its last seven games against Virginia.
- The total has hit the under in five of Virginia's last six games.
- The total has hit the under in each of Louisville's last five games against Virginia.

Virginia vs Louisville Odds

All NCAAF betting lines, odds and prop bets are available on FanDuel Sportsbook.
Moneyline: UVA: (+114) | LOU: (-140)
Spread: UVA: +2.5 (-108) | LOU: -2.5 (-112)
Total: 69.5 – Over: (-104) | Under: (-118)
Public (Spread) Betting Percentages via oddsFire: UVA: (N/A) | LOU: (N/A)

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Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.