USC vs Colorado Point Spread, Over/Under, Moneyline and Betting Trends for College Football Week 5 Game

Larry Rupp
USC Trojans vs Colorado Buffaloes prediction, odds, spread, over/under and betting trends for college football Week 5 game.
USC Trojans vs Colorado Buffaloes prediction, odds, spread, over/under and betting trends for college football Week 5 game. / Katelyn Mulcahy/Getty Images
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Week 5's slate of NCAA college football games includes a showdown between the USC Trojans and Colorado Buffaloes.

Here's everything you need to know before placing your bet for this game on FanDuel Sportsbook.

USC vs Colorado Point Spread

The Trojans are 7.5-point road favorites against the Buffaloes. USC is -110 to cover the spread, while Colorado is -110 to cover as the 7.5-point underdog.

USC vs Colorado Over/Under

The over/under for the USC vs Colorado Week 5 college football matchup is set at 50.5, with -115 odds on the over and -105 odds on the under.

USC vs Colorado Moneyline

The Trojans vs Buffaloes moneyline has USC as a -340 favorite, while Colorado is the +265 underdog at home.

USC vs Colorado Betting Trends

- USC is 14-0 in 14 all-time head-to-head matchups against Colorado.
- USC defeated Colorado, 35-31, in their last meeting on Oct. 25, 2019.
- The total has hit the under in seven of USC's last 10 games.
- The total has hit the under in four of Colorado's last five games against USC.
- USC is 6-0 in its last six road games.
- Colorado is 1-5 against the spread (ATS) in its last six games.

USC vs Colorado Odds

All NCAAF betting lines, odds and prop bets are available on FanDuel Sportsbook.
Moneyline: USC: (-340) | COLO: (+265)
Spread: USC: -7.5 (-110) | COLO: +7.5 (-110)
Total: 50.5 – Over: (-115) | Under: (-105)
Public (Spread) Betting Percentages via oddsFireUSC: (N/A) | COLO: (N/A)


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Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

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