Rams vs Colts Prediction, Odds, Spread, Over/Under & Betting Trends for NFL Week 2 Game on FanDuel Sportsbook

Larry Rupp
Los Angeles Rams vs Indianapolis Colts prediction, odds, spread, over/under and betting trends for NFL Week 2 game.
Los Angeles Rams vs Indianapolis Colts prediction, odds, spread, over/under and betting trends for NFL Week 2 game. / Thearon W. Henderson/Getty Images
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Rams vs Colts Week 2 Game Info

NFL Regular Season — Week 1 Game
Los Angeles Rams (1-0, 0-0 Away) vs. Indianapolis Colts (0-1, 0-1 Home)
Date: Sunday, September 19, 2021
Time: 1:00 p.m. EST
Venue: Lucas Oil Stadium — Indianapolis, IN
Coverage: FOX

Rams vs Colts Odds & Spread

All NFL regular betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: LAR: (-198) | IND: (+166)
Spread: LAR: -3.5 (-115) | IND: +3.5 (-105)
Total: 48.5 — Over: (-105) | Under: (-115)
Public (Spread) Betting Percentages via oddsFire: LAR: (79%) | IND: (11%)
Odds to Win Super Bowl LVI: LAR: (+1300) | IND: (+4000)

Rams vs Colts Prediction & Pick

All NFL predictions and picks are from numberFire's projection model.
Prediction: Rams win (54.5%)

Rams vs Colts Betting Trends

- The Rams are 1-0 against the spread (ATS) this season.
- The total hit the over in the Rams' first game this season.
- Indianapolis is 0-1 ATS this season.
- The total hit the over in Indianapolis' first game this season.


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Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

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