Monday Night Football Fantasy Picks: Start 'Em, Sit 'Em for Bills vs Titans

Fantasy football picks for the Buffalo Bills vs Tennessee Titans Week 6 matchup, including Emmanuel Sanders, Julio Jones and Ryan Tannehill.
Fantasy football picks for the Buffalo Bills vs Tennessee Titans Week 6 matchup, including Emmanuel Sanders, Julio Jones and Ryan Tannehill. / Joshua Bessex/GettyImages

Monday Night Football Fantasy

Week 6 of the NFL slate concludes with a matchup between the Buffalo Bills and Tennessee Titans on Monday Night Football. FanDuel Sportsbook has the Bills as 5.5-point favorites, suggesting Tennessee may be playing catch-up.

MNF Fantasy Picks

If you need some help with your fantasy lineups, here's some start 'em, sit 'em advice for this Week 6 AFC showdown.

Emmanuel Sanders Fantasy

Start Emmanuel Sanders, Wide Receiver, Buffalo Bills: Emmanuel Sanders is coming off of his second 20-point PPR outing in three games. He's developed an obvious connection with Josh Allen, as the two have hooked up for four touchdowns in the past three weeks. Now he draws a matchup against a Titans defense giving up the most PPR points to wide receivers per game (47.36). Each one of the Bills' pass-catchers should thrive against a secondary that ranks in the bottom 10 in Football Outsiders' pass defense DVOA metric.

Julio Jones Fantasy

Start Julio Jones, WR, Tennessee Titans: Julio Jones will return from a two-game absence in Week 6, and it couldn't have come at a better time. Fellow wideout A.J. Brown, who's struggled with his own injury issues, is now questionable for this contest due to an illness. That could thrust Jones into being the No. 1 target for Ryan Tannehill with few other inspiring options. The Titans may be forced to air the ball out a ton as 5.5-point underdogs in this one, making Jones an attractive play. This week could be the perfect opportunity for the veteran to bounce back.

Devin Singletary Fantasy

Sit Devin Singletary, RB, Buffalo Bills: Devin Singletary is not the Bills RB managers should be starting right now. After racking up 17.1 PPR points in Week 2, Singletary has managed just 16.8 fantasy points combined over the last three weeks. Singletary has seen his snap share decline since Week 2 as well, bottoming out at 26% in Week 5. Zack Moss' snap share, meanwhile, is on the rise, including a notable 74% mark in Week 5. This backfield is known to pass the baton back and forth throughout the year, and it's clear Moss is leading the race for now.

Ryan Tannehill Fantasy

Sit Ryan Tannehill, QB, Tennessee Titans: Ryan Tannehill and the Titans' passing game has been lifeless to start the year. Tannehill is just QB23 in fantasy scoring this year due to struggles and injury woes affecting his receiving corps. Those issues could be a major factor again in Week 6 as top wideout A.J. Brown is dealing with an illness. Being down a star receiver is a terrible position to be in against a Bills defense allowing the second-fewest passing yards per game (173.4). Buffalo is also the league's stingiest in QB fantasy PPG (10.83), so avoid Tannehill like the plague.

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Isaiah De Los Santos is not a FanDuel employee. In addition to providing DFS gameplay advice, Isaiah De Los Santos also participates in DFS contests on FanDuel using his personal account, username zayyy05328. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.