Mississippi State vs LSU Prediction, Odds & Betting Trends for College Football Week 3 Game on FanDuel Sportsbook

Devon Platana
Mississippi State vs. LSU prediction, odds and betting trends for NCAA college football game.
Mississippi State vs. LSU prediction, odds and betting trends for NCAA college football game. / ASSOCIATED PRESS

Mississippi State vs LSU Week 3 Game Info

2022 NCAA College Football Game
Mississippi State Bulldogs (2-0, 0-0 SEC) vs. LSU Tigers (1-1, 0-0 SEC)
Date: Saturday, Sept. 17, 2022
Time: 6 p.m. ET
Venue: Tiger Stadium — Baton Rouge, LA
Coverage: ESPN

Week 3 of the 2022 NCAA college football season includes a showdown between the Mississippi State Bulldogs and LSU Tigers. The Bulldogs have got to be feeling themselves after their 39-17 victory over Arizona. Mississippi State quarterback Will Rogers put on a show for the fans, completing 39 passes for 313 yards and four touchdowns with an interception.

Meanwhile, LSU got its first win of the new season by defeating Southern, 65-17. The Tigers scored a total of nine TDs in the victory, including three through the air, five on the ground and one that came off an interception.

Mississippi State vs LSU Odds & Spread

All NCAAF betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: MSST: (-142) | LSU: (+118)
Spread: MSST: -2.5 (-120) | LSU: +2.5 (-102)
Total: 53.5 — Over: (-108) | Under: (-112)

Mississippi State enters this contest as the favorite on the spread. This 6 p.m. ET clash also features a total of 53.5, which is on the higher side compared to the rest of this week's college football projected totals.

Mississippi State vs LSU Prediction & Pick

Wins have been tough for Mississippi State to come by when LSU is involved. The Bulldogs have lost 31 of their last 37 games against the Tigers, including their last meeting in 2021 by a final score of 28-25. Furthermore, the Bulldogs are only 2-11 straight up in their last 13 trips to Tiger Stadium.

Having said that, I predict that Mississippi State will get the win here. A big part of LSU's offense is its run game, which could be in trouble against a Bulldogs defense giving up just 84.5 rushing yards per game in 2022. I expect that Mississippi State's D will come to play, ending with a close-fought victory in the road team's favor.

Final Score Prediction: Mississippi State: 28 | LSU: 24

Mississippi State vs LSU Betting Trends

- Mississippi State is 3-17 straight up in its last 20 games against LSU.
- LSU is 8-4 against the spread (ATS) in its last 12 Week 3 matchups.
- The total has hit the under in four of Mississippi State's last five games played in September.
- The total has hit the under in six of LSU's last seven games against Mississippi State.

Mississippi State vs LSU Best Bet

All NCAAF betting lines, odds and prop bets are available on FanDuel Sportsbook.

As shown in the above trends, Mississippi State and LSU have often combined for the under in recent meetings. That's something that I predict will happen again considering that the average total of their last seven games has been 47 points.

With both schools' defenses playing well in the first two weeks, expect another low-scoring game here.

Bet: Under 53.5 Points (-112)

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Devon Platana is not a FanDuel employee. In addition to providing DFS gameplay advice, Devon Platana also participates in DFS contests on FanDuel using his personal account, username PepeSilvia0. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.