LOS ANGELES, CA - SEPTEMBER 01:  Quarterback JT Daniels #18 gets a pat on the back from wide receiver Amon-Ra St. Brown #8  and a fist pump from head coach Clay Helton of the USC Trojans during warm up before the game against the UNLV Rebels in the game at the Los Angeles Memorial Coliseum on September 1, 2018 in Los Angeles, California.  (Photo by Jayne Kamin-Oncea/Getty Images)

5 Most Intriguing Week 2 College Football Spreads

Cover Photo: Jayne Kamin-Oncea/Getty Images 

Week 2 of the college football season has arrived. There are some big games this week and some intriguing lines that come with it. With so many games and so many teams vying for early playoff positioning, here are some lines to keep an eye on Saturday. 

5. New Mexico Lobos (+35) at No. 5 Wisconsin Badgers, 12:00 p.m.

Dylan Buell/Getty Images 

Wisconsin is expected to be a powerhouse this season and didn't disappoint in their Week 1 thumping of Western Kentucky. Facing an opponent this week in New Mexico, which finished in the cellar in the Mountain West last season and won just three games over the course of the year, they're not much better. The line may scare people away, but the Badgers could certainly cover this one.

4. FIU Panthers (+2) at Old Dominion Monarchs, 7:30 p.m.

Mark Brown/Getty Images 

FIU may have been considered the favorites here at one point, but took a huge step backwards after tragedy struck the team. Star running back Anthony Jones and offensive lineman Mershawn Miller were shot during a drive-by. While Jones is in stable condition, he will clearly not be able to play against Old Dominion. He was huge for this offense last week, rushing for two scores, making it hard to picture how his team will respond. They'll either rally together and bring one home for their teammates who were shot, or fail to find a way to replace their star offensive player and collapse in his absence.

3. Kentucky Wildcats (+13.5) at No. 25 Florida Gators, 7:30 p.m.

Sam Greenwood/Getty Images

Right now, Florida has a lot to prove. Yes, they're a powerhouse of a program and much better than Kentucky, but they're currently just 25th in the nation and are far from a contender. That two-touchdown line is high, but this is the same team that almost won by 50 last week. And there is the fact that Florida has beaten the Wildcats 31 straight times. History is always something to consider. 

2. South Alabama Jaguars (+31.5) at Oklahoma State Cowboys, 8 p.m.

Brett Deering/Getty Images

As we know from last week's 58-point outburst, the Oklahoma State Cowboys can put up big points. They may not be ranked, but they're a team who can score in a hurry. And the Cowboys will have to, considering how lofty that line is. Plus, it's almost impossible for an underdog to come into Stillwater and compete.

1. No. 17 USC Trojans (+6) at No. 10 Stanford Cardinal, 8:30 p.m.

Jayne Kamin-Oncea/Getty Images 

Stanford's opening act against San Diego State last weekend came with a shockingly slow start at the hands of star running back Bryce Love's stagnant performance. The preseason Heisman favorite laid an egg against the Aztec defense with just 29 yards on 18 carries and no scores. USC's potential and legitimacy are both a bit of a question mark heading into Week 2 of the 2018-19 season though. 

The Trojans lost their two-year starter at quarterback in Sam Darnold to the 2018 NFL Draft and have replaced him with a true freshman in JT Daniels. Daniels was solid against UNLV in Week 1, but USC had a lot riding on Darnold's arm for offensive success last season. Saturday's outcome will likely boil down to whether Stanford's Love can outperform USC's Daniels, or the other way around. 

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