49ers vs Saints Predictions and Expert Picks for Week 10 NFL Game

The New Orleans Saints are riding high off a huge win in Week 9, which sometimes sets a team up for a let-down spot the following weekend. The San Francisco 49ers will be the franchise attempting to pull off that upset, as the Saints look to keep the eye on the NFC South prize.

Let's see who the experts are taking as we head down to New Orleans, Louisiana in Week 10.

49ers vs Saints Picks Week 10

CBS Sports picks are from their panel of experts, numberFire picks are from their NFL game projections, Sporting News picks are from Vinnie Iyer, and betting favorites are from FanDuel Sportsbook's Week 10 NFL odds.

Winner:
CBS Sports: Saints (4)
numberFire: Saints
Sporting News: Saints
Betting Favorite: Saints

Against the Spread:
CBS Sports: Saints (3), 49ers (1)
Sporting News: Saints

After witnessing the hurting that the Saints put on the Tampa Bay Buccaneers last weekend, no one feels confident picking against them at home versus the banged up Niners. Only one expert even thinks the 49ers can cover the spread here.

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Michael Obermuller is not a FanDuel employee. In addition to providing DFS gameplay advice, Michael Obermuller also participates in DFS contests on FanDuel using his personal account, username king_mizzard. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.