Monday Night Football Fantasy Picks: Start 'Em, Sit 'Em for Chiefs vs Bills

Max Staley
Clyde Edwards-Helaire is one of the top fantasy picks for the Chiefs-Bills matchup.
Clyde Edwards-Helaire is one of the top fantasy picks for the Chiefs-Bills matchup. / Todd Olszewski/Getty Images

Two of the AFC's most electric QBs will face off in the first Monday Night Football Game of Week 6. Patrick Mahomes' Kansas City Chiefs will travel to Buffalo to face Josh Allen's Buffalo Bills. Kansas City is currently a 4-point road favorite in this one, according to FanDuel Sportsbook.

If you need some fantasy help, here's some start 'em, sit 'em advice for what's shaping up to be the best game of Week 6.

Who Should I Start Fantasy Football

Start Clyde Edwards-Helaire, RB, Kansas City Chiefs: Clyde Edwards-Helaire started out his NFL career with a bang, racking up 19.8 fantasy points in the first game of the year. While he's remained solid since then, he hasn't exactly been the no-doubt RB1 many were hoping for. He's also coming off back-to-back career lows in fantasy points (12.1, 11.0). It may be tempting to think about benching CEH against a stout defense like Buffalo's due to the Le'Veon Bell addition, but Bell won't be active in this one. Plus, CEH is still a really talented back seeing 21.6 opportunities (carries plus targets) per game while playing in the league's best offense. That's going to drop as Bell gets integrated into the offense, but he's still a great option this week.

Start Devin Singletary, RB, Buffalo Bills: With Zack Moss likely to return to the lineup in Week 6, you might be hesitant to start Devin Singletary this week. But a slightly reduced role shouldn't matter too much against this Chiefs' defense. Kansas City was terrible against the run last year and it's still a weakness for the team, as the Chiefs are the NFL's fifth-worst unit against the rush, per Football Outsiders' DVOA metrics. Kansas City is also surrendering top-10 fantasy production to the position.

Sit Mecole Hardman, WR, Kansas City Chiefs: Mecole Hardman looks poised for an uptick in value now that Sammy Watkins is out, but he might not be as valuable as you think. He played a season-high 69% of the team's snaps in Week 5, but the increased role didn't translate into much production, finishing with 2 catches for 50 yards on 3 targets. That's thanks in large part to Demarcus Robinson, who Hardman still appears to be splitting time with. Robinson played just 1 fewer snap than Hardman in Week 5, and he actually out-targeted him 4 to 3. These two will likely continue to cannibalize each other's value going forward. It'll be tough to trust either one.

Sit John Brown, WR, Buffalo Bills: Kansas City is definitely beatable on the ground, but it's been pretty tough to throw on this team recently. The Chiefs are the league's second-best unit against the pass by DVOA, and they're also surrendering the sixth-fewest fantasy points per game to opposing wide receivers. Stefon Diggs has simply been too good to even think about benching, but the same cannot be said for John Brown. He was inactive last week due to a calf injury, and even if he's deemed 100%, it'll be hard to feel good about starting any of the Bills' pass-catchers other than Diggs in this one.

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Max Staley is not a FanDuel employee. In addition to providing DFS gameplay advice, Max Staley also participates in DFS contests on FanDuel using his personal account, username mstaley1212. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.