The Duel

Bills vs Cardinals Point Spread, Over/Under, Moneyline and Betting Trends for NFL Week 10

Zach Brunner
Bills vs Cardinals point spread, over/under, moneyline and betting trends for Week 10.
Bills vs Cardinals point spread, over/under, moneyline and betting trends for Week 10. / Norm Hall/Getty Images
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The Buffalo Bills hit the road to face the Arizona Cardinals at State Farm Stadium in Week 10 NFL action on Sunday.

Here's everything you need to know before placing your bet for this game onFanDuel Sportsbook.

Bills vs Cardinals Point Spread

The Bills are 1.5-point road underdogs. The Cardinals are 1.5-point home favorites, with -120 odds to cover the spread. Buffalo has -102 odds to cover.

Bills vs Cardinals Over/Under

The over/under for the Bills vs Cardinals Week 10 matchup is set at 55.5 total points, with -115 odds on the over and -105 on the under.

Bills vs Cardinals Moneyline

The Bills vs Cardinals moneyline has Buffalo as +114 road underdogs, while Arizona is the -134 favorite at home.

Bills vs Cardinals Betting Trends

- Buffalo is 1-4 against the spread (ATS) in its last five games.
- The total has hit the over in seven of Buffalo’s last nine games.
- The total has hit the over in five of Arizona’s last six games against Buffalo.
- Arizona is 5-14-1 straight up in its last 20 home games.

Bills vs Cardinals Odds

All betting lines, odds and prop bets are available on FanDuel Sportsbook.
Moneyline: BUF: (+114) | ARI: (-134)
Spread: BUF: +1.5 (-102) | ARI: -1.5 (-120)
Total: 55.5 – Over: (-115) | Under: (-105)
Public (Spread) Betting Percentages via oddsFireBUF: (71%) | ARI: (29%)
Odds to Win Super Bowl LV: BUF: (+2400) | ARI: (+2900)


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