NFL - Odds & Predictions

Bills vs Patriots Point Spread, Over/Under, Moneyline and Betting Trends for NFL Week 16 Game

Devon Platana
Bills vs Patriots point spread, over/under, moneyline and betting trends for Week 16 NFL game.
Bills vs Patriots point spread, over/under, moneyline and betting trends for Week 16 NFL game. / Maddie Meyer/GettyImages
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Week 16's slate of games includes a showdown between the Buffalo Bills and New England Patriots.

Here's everything you need to know before placing your bet for this game on FanDuel Sportsbook.

Bills vs Patriots Point Spread

The Patriots are 1.5-point favorites against the Bills. New England is -114 to cover the spread, while Buffalo is -106 to cover as a 1.5-point underdog.

Bills vs Patriots Over/Under

The over/under for the Bills vs Patriots Week 16 NFL matchup is set at 43.5, with -110 odds on the over and -110 odds on the under.

Bills vs Patriots Moneyline

The Bills vs Patriots moneyline has New England as a -126 favorite, while Buffalo is a +108 underdog on the road.

Bills vs Patriots Betting Trends

- Buffalo is 4-16 straight up in its last 20 games against New England.
- The total has hit the over in four of Buffalo's last six games.
- New England is 7-1 against the spread (ATS) in its last eight games.
- The total has hit the over in four of New England's last five home games.

Bills vs Patriots Prediction

All NFL predictions and picks are from numberFire's projection model.
Prediction: New England Patriots win (63.2%)

Bills vs Patriots Odds

All NFL betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: BUF: (+108) | NE: (-126)
Spread: BUF: +1.5 (-106) | NE: -1.5 (-114)
Total: 43.5 — Over: (-110) | Under: (-110)
Odds to Win Super Bowl LVI: BUF: (+1100) | NE: (+1100)


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Devon Platana is not a FanDuel employee. The views expressed in his articles are the author's alone and do not necessarily reflect the views of FanDuel.

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