3 Best Prop Bets for Titans vs Bills Monday Night Football Week 2

Isaiah De Los Santos
Best prop bets for Tennessee Titans vs Buffalo Monday Night Football Week 2 game.
Best prop bets for Tennessee Titans vs Buffalo Monday Night Football Week 2 game. / (AP Photo/John McCoy)

Week 2 of the 2022 NFL season wraps up with a pair of Monday Night Football clashes, including the Tennessee Titans vs. Buffalo Bills. There should be plenty of scoring with an over/under of 47.5 for this matchup, though this contest could end up being a one-sided affair.

Here are three of the best prop bets for Titans-Bills, courtesy of NFL odds on FanDuel Sportsbook.

Titans vs Bills MNF Prop Bets Tonight

1. Derrick Henry - Rushing Yards: Under 85.5 (-110)

There's no denying Derrick Henry is a dominant talent, but his just decent Week 1 showing prompts questions of how much he has left in the tank. Henry rushed for 82 yards on 21 attempts against the New York Giants in Week 1, while Christian McCaffrey (102 yards on just 15 attempts) lit that same unit up on Sunday. Henry also draws a matchup that's far from ideal with the Bills' intimidating front line ready to make his night difficult. Buffalo ranks No. 1 in Football Outsiders' rush-defense DVOA metric after the first week of the season. With the Titans slated as whopping 10-point underdogs, it's very likely they're forced to abdanon the run in order to keep up with the Bills' high-flying offense, which would leave fewer carries for Henry as a result. It's hard to see the All-Pro smashing this over against this defense.

2. Stefon Diggs - Anytime TD Scorer (+115)

Stefon Diggs started the year off with a bang in Week 1, hauling in 8 receptions for 122 yards and 1 TD. However, he could take on an even bigger role for the Bills' offense in Week 2 with counterpart Gabriel Davis questionable due to an ankle injury. Davis is known for his ability to score, and the wideout being absent or even limited would make Diggs an ever clearer No. 1 target for Josh Allen. Diggs had no problem dominating Tennessee last season, recording 9 catches for 89 yards and a touchdown. The Titans showed they're susceptible to giving up big plays after letting Sterling Shepard score a 65-yard TD last week, so it'd be no surprise to see Diggs find the endzone in this one.

3. Robert Woods - Receiving Yards: Under 40.5 (-110)

Robert Woods clearly has some rust to shake off after returning from last season's ACL tear. Bobby Trees recorded a meager 1 reception for 13 yards in Week 1, but even more concerning was the fact he only garnered 2 targets. That seems to indicate Woods struggled to get open, and that could continue on Monday against this tough Bills secondary. Though they let Cooper Kupp go off for 128 yards in their last time out, Woods is far from his level, and the next-highest wide receiver only managed to secure 25 yards. It's also likely Buffalo focuses on blanketing Woods in order to make the Titans' less-established options beat them, so it could be another quiet night for the veteran.

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Isaiah De Los Santos is not a FanDuel employee. In addition to providing DFS gameplay advice, Isaiah De Los Santos also participates in DFS contests on FanDuel using his personal account, username zayyy05328. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.