49ers vs Rams Predictions and Expert Picks for Week 12 NFL Game

One of the NFC West's biggest rivalries will continue in Week 12 as with the 49ers taking on the Los Angeles Rams for the second time this season.

Here's what the experts are predicting for this matchup after the 49ers came away with a win in Week 6.

49ers vs Rams Picks Week 12

CBS Sports picks are from their panel of experts, numberFire picks are from their NFL game projections, Sporting News picks are from Vinnie Iyer, and betting favorites are from FanDuel Sportsbook's Week 12 NFL odds.

Winner:
CBS Sports: Rams (5)
numberFire: Rams
Sporting News: Rams
Betting Favorite: Rams -7

Against the Spread:
CBS Sports: 49ers (3), Rams (2)
Sporting News: 49ers

The Rams are the unanimous pick to win this game. Most of the experts do think the 49ers bring their best stuff for this rivalry game and keep it close.

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Jason Schandl is not a FanDuel employee. In addition to providing DFS gameplay advice, Jason Schandl also participates in DFS contests on FanDuel using his personal account, username Jaymun. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in his articles are the author's alone and do not necessarily reflect the views of FanDuel.