NFL - Odds & Predictions

49ers vs Jaguars Prediction, Odds, Spread, Over/Under & Betting Trends for NFL Week 11 Game on FanDuel

Larry Rupp
San Francisco 49ers vs Jacksonville Jaguars prediction, odds, spread, over/under and betting trends for NFL Week 11 game.
San Francisco 49ers vs Jacksonville Jaguars prediction, odds, spread, over/under and betting trends for NFL Week 11 game. / Lachlan Cunningham/GettyImages
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49ers vs Jaguars Week 11 Game Info

NFL Regular Season — Week 11 Game
San Francisco 49ers (4-5, 3-1 Away) vs. Jacksonville Jaguars (2-7, 2-3 Home)
Date: Sunday, November 21, 2021
Time: 1:00 p.m. EST
Venue: TIAA Bank Field — Jacksonville, FL
Coverage: FOX

49ers vs Jaguars Odds & Spread

All NFL regular betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: SF: (-290) | JAX: (+235)
Spread: SF: -6.5 (-115) | JAX: +6.5 (-105)
Total:
 45.5 — Over: (-105) | Under: (-115)
Odds to Win Super Bowl LVI: SF: (+7000) | JAX: (+100000)

49ers vs Jaguars Prediction & Pick

All NFL predictions and picks are from numberFire's projection model.
Prediction: San Francisco 49ers Win (68.9%)

49ers vs Jaguars Betting Trends

- San Francisco is 4-1straight up in its last five away games.
- The total has hit the over in four of San Francisco's last five games against an AFC opponent.
- Jacksonville is 4-2 against the spread (ATS) in its last six games.
- The total has hit the under in seven of Jacksonville's last eight games.


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Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

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