NFL - Fantasy

Week 13 Fantasy Picks: Start 'Em, Sit 'Em for 49ers vs Seahawks

Adam Taylor McKillop
Fantasy football picks for the San Francisco 49ers vs Seattle Seahawks Week 13 matchup, including Russell Wilson, Alex Collins and Brandon Aiyuk.
Fantasy football picks for the San Francisco 49ers vs Seattle Seahawks Week 13 matchup, including Russell Wilson, Alex Collins and Brandon Aiyuk. / Todd Olszewski/GettyImages
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The San Francisco 49ers look to make it four straight wins when they visit theirNFC West rivals Seattle Seahawks in Week 13. FanDuel Sportsbook has the 49ers slated as 3.5-point road favorites in this NFC West clash.

If you need some help with your fantasy lineups, here's some start 'em, sit 'em advice for this Week 13 showdown.

Brandon Aiyuk Fantasy

Start Brandon Aiyuk, WR, San Francisco 49ers: It's looking like Deebo Samuel won't be able to suit up in Week 13 and that leaves a huge opportunity for Brandon Aiyuk. Aiyuk owns just 48 targets on the year, but Samuel's 29% target share leaves a mass of opportunity. Aiyuk has been in good form lately, averaging 6.4 targets, 4.6 receptions and 67.2 receiving yards over his last five. Seattle allows the second-most passing yards (274.1) per game this season, so if Samuel isn't active, expect a good showing from Aiyuk.

Alex Collins Fantasy

Start Alex Collins, RB, Seattle Seahawks: Alex Collins flopped in his Week 12 start, but that shouldn't necessarily scare away fantasy managers. The 49ers rank second in Football Outsiders' pass-defense DVOA metric and Seattle will look to succeed on the ground instead. Prior to Week 12, Collins had put together five straight starts averaging 14.2 rushing attempts and 53.6 rushing yards per contest. None of Seattle's playmakers are great fantasy options, but consider Collins worth a FLEX start in Week 13.

Jeff Wilson Fantasy

Sit Jeff Wilson, RB, San Francisco 49ers: Elijah Mitchell rules the 49ers running back depth chart and that leaves Jeff Wilson on the outside looking in. He's seen just 12 rushing attempts during Mitchell's last two starts, compared to Mitchell's impressive 54 attempts. The Seahawks also rank 11th in Football Outsiders' rush-defense DVOA metric meaning there's not enough juice for San Francisco's clear-cut backup in Week 13.

Russell Wilson Fantasy

Sit Russell Wilson, QB, Seattle Seahawks: Russell Wilson finished as QB9 last week, but unfortunately that's been one of his best performances of the year. He averages the 17th-most fantasy points per game this season, which remains relevant only in two-QB leagues. Plus, the 49ers boast a secondary that ranks second in Football Outsiders' pass-defense DVOA metric and allows the sixth-fewest passing yards per contest (207.3).


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Adam Taylor McKillop is not a FanDuel employee. In addition to providing DFS gameplay advice, Adam Taylor also participates in DFS contests on FanDuel using his personal account, username atmckillop. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

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