Week 12 Fantasy Picks: Start 'Em, Sit 'Em for Bills vs Saints (Thanksgiving Day Game)

The Buffalo Bills will look to keep pace with the New England Patriots in the AFC East when they travel to take on the New Orleans Saints on Thanksgiving Day. FanDuel Sportsbook has the Bills slated as 5.5-point road favorites in a game filled with playmakers on both sides of the football.

If you need some help with your fantasy lineups, here's some start 'em, sit 'em advice for this Week 12 showdown.

Josh Allen Fantasy

Start Josh Allen, QB, Buffalo Bills: Fantasy managers have had the right to be a bit disappointed with quarterback Josh Allen over the last three weeks. The Bills' starter has thrown five interceptions compared to just 4 touchdowns during that span. That doesn't mean he shouldn't still be started, though. Allen ranks as the QB3 in fantasy scoring despite his recent issues and draws a favorable matchup in Week 12. New Orleans ranks in the middle of the pack against the pass and have been torched by mobile QBs. In fact, the Saints just allowed 3 rushing touchdowns to Jalen Hurts in Week 11. Look for Allen to use his legs in order to post QB1 numbers on Thursday.

Alvin Kamara Fantasy

Start Alvin Kamara, RB, New Orleans Saints: There should be no hesitation with starting Alvin Kamara if he's healthy enough to suit up in Week 12. The Pro Bowl ball-carrier has rushed for a touchdown in three of his last four games played and is averaging a reliable 18.3 carries per contest this season. While the Bills rank No. 1 in pass defense DVOA rating, they find themselves at No. 12 against the run. There's an opportunity here for Kamara to control the game on the ground as that is the Saints' best chance of winning this game. He should be started with confidence in Week 12.

Zack Moss & Devin Singletary Fantasy

Sit Zack Moss & Devin Singletary, RB, Buffalo Bills: The Saints have been shutting down opposing rushing attacks all season and that does not bode well for Zack Moss & Devin Singletary in fantasy football. These two have combined for just 114 rushing yards on 29 carries over the last three weeks and even got out-carried by veteran Matt Breida in Week 11. New Orleans has posted the best rush defense DVOA rating in the NFL and is allowing the third-fewest PPR fantasy points to opposing RBs. Simply put, this is not the matchup to slide any Buffalo RB into a FLEX spot.

Trevor Siemian Fantasy

Sit Trevor Siemian, QB, New Orleans Saints: Quarterback Trevor Siemian finished Week 11 as the QB4 in fantasy scoring after he racked up 214 passing yards and 4 total touchdowns (3 passing & 1 rushing). However, it's important to point out that he did most of his damage in garbage time when the Saints were stuck playing catch up. Siemian draws a nightmare matchup on Thanksgiving going up against a Buffalo team that has posted the No. 1 pass defense DVOA rating in the NFL. Overall, the Bills are giving up the fewest fantasy points to opposing QBs this season. Siemian should be avoided across all league formats.

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Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.