Pittsburgh vs Duke Point Spread, Over/Under, Moneyline & Prediction for College Football Week 10

Week 10's slate of NCAA college football games includes a showdown between the Pittsburgh Panthers and Duke Blue Devils.

Here's everything you need to know before placing your bet for this game on FanDuel Sportsbook.

Pittsburgh vs Duke Point Spread

The Panthers are 21.5-point road favorites against the Blue Devils. Pittsburgh is -106 to cover the spread, while Duke is -114 to cover as the 21.5-point underdog.

Pittsburgh vs Duke Over/Under

The over/under for the Pittsburgh vs Duke Week 10 college football matchup is set at 64.5, with -118 odds on the over and -104 odds on the under.

Pittsburgh vs Duke Moneyline

The Panthers vs Blue Devils moneyline has Pittsburgh as a -1400 favorite, while Duke is the +760 underdog at home.

Pittsburgh vs Duke Betting Trends

- Pittsburgh is 15-9 straight up in 24 all-time head-to-head matchups against Duke.
- Pittsburgh defeated Duke, 33-30, during their most recent meeting on Oct. 5, 2019.
- Pittsburgh is 5-0 against the spread (ATS) in its last five games against Duke.
- The total has hit the over in 13 of Pittsburgh's last 16 games.
- Duke is 0-9 straight up in its last nine games against an ACC opponent.
- The total has hit the over in five of Duke's last seven games against Pittsburgh.

Pittsburgh vs Duke Prediction

All NCAAF predictions & expert picks are according to numberFire.
Prediction: Pittsburgh Wins (98.7%)

Pittsburgh vs Duke Odds

All NCAAF betting lines, odds and prop bets are available on FanDuel Sportsbook.
Moneyline: PITT: (-1400) | DUKE: (+760)
Spread: PITT: -21.5 (-106) | DUKE: +21.5 (-114)
Total: 64.5 – Over: (-118) | Under: (-104)

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Devon Platana is not a FanDuel employee. The views expressed in his articles are the author's alone and do not necessarily reflect the views of FanDuel.