With the Kansas City Chiefs falling to the Indianapolis Colts in Week 5, there are now only two remaining undefeated teams, the New England Patriots and San Francisco 49ers.
With Tom Brady and his former backup Jimmy Garoppolo looking to remain undefeated, here are three Week 6 matchups that can potentially be exploited against the spread (ATS).
All odds, spread and prop bets available via FanDuel Sportsbook.
1. San Francisco 49ers (+3.5) vs. Los Angeles Rams
Through four games played, the 49ers have looked nothing like the team we saw last season. The thing is, neither have the Los Angeles Rams. While the 49ers were the fifth-worst scoring defense in the NFL last year, they are now No. 1 in Football Outsiders' DVOA pass defense rankings, are surrendering the fourth-fewest points per game (PPG) in the NFL, and rank fifth in the NFL with a 9.2 sack percentage. The Rams, meanwhile, opened the 2018 season scoring more than 30 points in five consecutive games, but they've only done that once through five weeks in 2019. Los Angeles has turned the ball over on 18.6 percent of its drives (fourth worst in the NFL), and will have to contend with a San Francisco defense forcing a turnover on a league-best 21.3 percent of drives.
2. New York Giants vs. New England Patriots (-16.5)
There are no shortage of stats that prove just how dominant the Patriots have been through five weeks. Their five wins this season have come by an average margin of 24.2 PPG, and New England has won its two home games by 23.0 PPG. Two of the New York Giants' three losses have come by 18 points, and they could struggle to stay competitive against a defense that's off to a historically great start.
3. New Orleans Saints (+1) vs. Jacksonville Jaguars
Gardner Minshew II will likely grab all the headlines, but Teddy Bridgewater has quietly held his own while filling in for Drew Brees. The New Orleans Saints are 3-0 in his three starts, and Bridgewater is coming off his best game of the season (314 yards, four TDs in Week 5). The Jacksonville Jaguars pass defense isn't quite the dominant unit it used to be, as they are the No. 18 in pass defense DVOA. Minshew will likely find a way to keep this game close, as he has in all five of his starts, but Bridgewater and the Saints are playing too well to ignore, even on the road.
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Max Staley is not a FanDuel employee. In addition to providing DFS gameplay advice, Max Staley also participates in DFS contests on FanDuel using his personal account, username mstaley1212. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.