NFL Week 2 Picks & Predictions Against the Spread From The Duel Staff

The 2021 NFL season kicked off last week in an exciting fashion, and the editors at The Duel are making against the spread (ATS) picks for each game. You can follow along, check it out, or fade us throughout the season.

NFL Week 2 Predictions

We have full betting previews for each matchup below along with the betting lines from FanDuel Sportsbook. We’ll update this with records on a weekly basis and make picks for every round of the playoffs through the Super Bowl.

Without further ado, here are our picks.

NFL Expert Picks Against the Spread

Note: All betting lines and odds are from FanDuel Sportsbook, as of Wednesday Sept. 15 at 4 p.m. EST.

Giants vs Washington Picks

Giants (+3) vs Washington (-3) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Washington
- Taylor McKillop: Giants
- David Kaestle: Giants
- Isaiah De Los Santos: Giants
- Jason Schandl: Washington
- Max Staley: Washington

Raiders vs Steelers Picks

Raiders (+5.5) vs Steelers (-5.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Raiders
- Taylor McKillop: Steelers
- David Kaestle: Steelers
- Isaiah De Los Santos: Raiders
- Jason Schandl: Steelers
- Max Staley: Raiders

Bengals vs Bears Picks

Bengals (+3) vs Bears (-3) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Bengals
- Taylor McKillop: Bengals
- David Kaestle: Bengals
- Isaiah De Los Santos: Bengals
- Jason Schandl: Bengals
- Max Staley: Bengals

Texans vs Browns Picks

Texans (+12.5) vs Browns (-12.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Texans
- Taylor McKillop: Texans
- David Kaestle: Texans
- Isaiah De Los Santos: Browns
- Jason Schandl: Browns
- Max Staley: Texans

Rams vs Colts Picks

Rams (-4) vs Colts (+4) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Colts
- Taylor McKillop: Rams
- David Kaestle: Rams
- Isaiah De Los Santos: Rams
- Jason Schandl: Colts
- Max Staley: Rams

Bills vs Dolphins Picks

Bills (-3.5) vs Dolphins (+3.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Bills
- Taylor McKillop: Bills
- David Kaestle: Bills
- Isaiah De Los Santos: Dolphins
- Jason Schandl: Dolphins
- Max Staley: Bills

Patriots vs Jets Picks

Patriots (-5.5) vs Jets (+5.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Patriots
- Taylor McKillop: Jets
- David Kaestle: Jets
- Isaiah De Los Santos: Jets
- Jason Schandl: Patriots
- Max Staley: Patriots

49ers vs Eagles Picks

49ers (-3.5) vs Eagles (+3.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: 49ers
- Taylor McKillop: 49ers
- David Kaestle: 49ers
- Isaiah De Los Santos: 49ers
- Jason Schandl: Eagles
- Max Staley: 49ers

Saints vs Panthers Picks

Saints (-3.5) vs Panthers (+3.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Saints
- Taylor McKillop: Saints
- David Kaestle: Saints
- Isaiah De Los Santos: Panthers
- Jason Schandl: Saints
- Max Staley: Saints

Broncos vs Jaguars Picks

Broncos (-6) vs Jaguars (+6) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Broncos
- Taylor McKillop: Jaguars
- David Kaestle: Broncos
- Isaiah De Los Santos: Broncos
- Jason Schandl: Jaguars
- Max Staley: Broncos

Vikings vs Cardinals Picks

Vikings (+3.5) vs Cardinals (-3.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Cardinals
- Taylor McKillop: Cardinals
- David Kaestle: Cardinals
- Isaiah De Los Santos: Cardinals
- Jason Schandl: Cardinals
- Max Staley: Cardinals

Falcons vs Buccaneers Picks

Falcons (+11.5) vs Buccaneers (-11.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Falcons
- Taylor McKillop: Buccaneers
- David Kaestle: Buccaneers
- Isaiah De Los Santos: Buccaneers
- Jason Schandl: Buccaneers
- Max Staley: Falcons

Cowboys vs Chargers Picks

Cowboys (+2.5) vs Chargers (-2.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Chargers
- Taylor McKillop: Cowboys
- David Kaestle: Chargers
- Isaiah De Los Santos: Cowboys
- Jason Schandl: Chargers
- Max Staley: Chargers

Titans vs Seahawks Picks

Titans (+5.5) vs Seahawks (-5.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Seahawks
- Taylor McKillop: Titans
- David Kaestle: Seahawks
- Isaiah De Los Santos: Titans
- Jason Schandl: Titans
- Max Staley: Titans

Chiefs vs Ravens Picks

Chiefs (-3.5) vs Ravens (+3.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Chiefs
- Taylor McKillop: Chiefs
- David Kaestle: Chiefs
- Isaiah De Los Santos: Chiefs
- Jason Schandl: Chiefs
- Max Staley: Chiefs

Lions vs Packers Picks

Lions (+11.5) vs Packers (-11.5) Betting Preview

Staff Picks (ATS):
- Brian Giuffra: Packers
- Taylor McKillop: Packers
- David Kaestle: Packers
- Isaiah De Los Santos: Lions
- Jason Schandl: Packers
- Max Staley: Lions

Staff Records (ATS):
- Taylor McKillop: 6-9 (40.00%)
- David Kaestle: 6-9 (40.00%)
- Isaiah De Los Santos: 7-8 (46.67%)
- Jason Schandl: 9-6 (60.00%)
- Max Staley: 9-6 (60.00%)

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David Kaestle is not a FanDuel employee. In addition to providing DFS gameplay advice, David also participates in DFS contests on FanDuel using his personal account, username davekaestle. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.