The first slate of games from the 2019 NFL season brought us some pretty interesting results. While the favorites took care of business, for the most part, the Cleveland Browns were the largest favorite (5.5 points) to enter Week 2 without a win.
With that in mind, let's take a look at some against the spread (ATS) matchups that could potentially be exploited in Week 2.
*All odds via FanDuel Sportsbook.
3. Minnesota Vikings (+3) vs. Green Bay Packers
Somewhat surprisingly, the Minnesota Vikings have gone 3-0-1 straight up in their last four games against the Green Bay Packers. Minnesota has played two road games against Green Bay during that span, and would have covered this spread in each, winning, 16-0, in 2017 and tying the Packers, 27-27, last season. Aaron Rodgers didn't play in the game in 2017, but he got off to a shaky start against the Chicago Bears in Week 1, and is facing a similarly loaded Vikings defense here. Unless the Green Bay offense looks completely different in Week 2, Dalvin Cook and the rest of Minnesota's offense could score enough to at least keep this game within three.
2. Los Angeles Chargers (-2.5) vs. Detroit Lions
The Detroit Lions got off to a great start against what projects to be one of the worst teams in football in the Arizona Cardinals, but their finish was concerning. Detroit allowed Arizona to score 18 points in the fourth quarter alone, as the Cardinals fought back from a 17-3 halftime deficit. While Matthew Stafford's 385-yard performance is encouraging, it's tough to separate his game from the defense that he was playing. Arizona surrendered 26.6 points per game (PPG) in 2018, and is now playing without top cornerback Patrick Peterson, who is out due to suspension. Stafford could struggle to move the ball against a Los Angeles Chargers defense that held the Indianapolis Colts to 190 passing yards in Week 1.
1. New Orleans Saints (+2.5) vs. Los Angeles Rams
If the latest regular-season meeting between these two is any indication, the New Orleans Saints could have an advantage. The Saints defeated the Los Angeles Rams, 45-35, in 2018. The next meeting between these two was the now-infamous NFC Championship game, which the Saints lost, 26-23, primarily due to a missed pass interference call on the Rams. Jared Goff also didn't look great to open the 2019 season, missing a ton of open receivers and throwing for 189 yards on just 4.8 yards per attempt. New Orleans will almost certainly be looking for revenge here, and has a good shot at keeping this game within three points.
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