Every team in the NFL already knows which teams they will be facing during the 2022 season, just not the specific dates and start times. That will be revealed at 8 p.m. ET on NFL Network on May 12. The Tennessee Titans also know that their schedule will be one of the the toughest ones in the league.
Mike Clay of ESPN highlighted how difficult Tennessee's road to a potential AFC South title is going to be when he revealed it has the seventh-hardest schedule by his grade. Head coach Mike Vrabel has his work cut out for him, so let's take a look at the three hardest matchups the Titans will have in 2022.
Tennessee Titans 2022 Schedule
1. @ Kansas City Chiefs
The Titans absolutely embarrassed the Kansas City Chiefs by a score of 27-3 when they played at Nissan Stadium this past season. It's safe to say quarterback Patrick Mahomes will be making sure that doesn't happen again when Tennessee comes to Arrowhead in the fall. The All-Pro signal-caller averages 301.4 passing yards per game and has thrown 151 touchdowns compared to 37 interceptions in his career. He could very well end up having a field day against a Titans defense that allowed the eighth-most passing yards per game in 2021 (247.2). The key to an upset win for Tennessee will be not letting that happen.
2. @ Buffalo Bills
The Buffalo Bills have to enter this year's matchup against the Tennessee Titans with a bit of a vendetta after dropping two straight regular season contests to them. Those losses certainly weren't on quarterback Josh Allen as he completed 69.3% of his pass attempts for 5 touchdowns (3 interceptions) during that span. Buffalo is one of the most balanced teams in the NFL as it posted the best DVOA rating and finished among the three teams in scoring last season (29.8 points per game). Add in the fact that Bills Mafia will be hungry to see a win at Highmark Stadium and this one could get ugly for Tennessee if they trail early.
3. @ Indianapolis Colts
This is not the same team that Tennessee went into Indianapolis and beat in overtime last season. They have ditched problematic quarterback Carson Wentz in favor of veteran Pro Bowler Matt Ryan. Ryan owns a career record of 2-1 against the Titans and averages 321.3 passing yards in those contests as well. Of course, Tennessee regularly leans on running back Derrick Henry to carry the load on offense. That makes it worth noting that Indianapolis posted the third-best rush defense DVOA rating last season and held Henry to 68 yards on 28 carries (2.4 average) at Lucas Oil Stadium back in October. This lines up to be an all-time classic battle between two divisional rivals.
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