NFL News and Rumors

Full Bills 2022 Schedule: List of Buffalo Opponents This NFL Season

Larry Rupp
Buffalo Bills football schedule for the 2022-23 NFL season.
Buffalo Bills football schedule for the 2022-23 NFL season. / David Butler II-USA TODAY Sports

The 2022-23 NFL regular-season schedule will be released on Thursday, May 12. The official release will let the Buffalo Bills know when and where they'll play throughout the year, since they already know who their opponents are.

2022 Bills Schedule

Here's everything we know so far about the Bills' schedule in 2022.

Buffalo Bills Football Schedule 2022

Buffalo will find out its entire schedule for the 2022-23 regular season on Thursday, May 12. The official schedule release is slated to air on NFL Network at 8 p.m. ET. This article will be updated once the full schedule has been released.

Bills Week 1 Opponent

The Buffalo Bills' Week 1 matchup has not been officially revealed yet. Last season, they opened with a home game against the Pittsburgh Steelers on Sunday Sept. 12, 2021.

Bills 2022 Strength of Schedule

According to ESPN's Mike Clay, the Bills have the 15th-easiest schedule in the NFL for the 2022 campaign.

Bills Home Games 2022

- New England Patriots
- Miami Dolphins
- New York Jets
- Green Bay Packers
- Minnesota Vikings
- Pittsburgh Steelers
- Cleveland Browns
- Tennessee Titans

Bills Away Games 2022

- New England Patriots
- Miami Dolphins
- New York Jets
- Baltimore Ravens
- Cincinnati Bengals
- Chicago Bears
- Detroit Lions
- Kansas City Chiefs
- Los Angeles Rams

Bills Opponents Record 2022

The Bills' opponents went 147-140-2 during the 2021-22 NFL season.

Bills 17th Game Opponent

The NFL officially added an extra 17th game to the schedule starting in 2021. It has been revealed that the Bills will travel to take on the Los Angeles Rams in that contest.

Bills Super Bowl Odds

The Bills are currently +650 (No. 1) in FanDuel Sportsbook's latest Super Bowl odds.

Bills Win Total Odds

Buffalo is listed with a win total of 11.5 for the 2022-23 regular season. The Bills are -115 to hit the over, and -105 to hit the under.

Bills Win Total Prediction 2022

The Bills signed three free agents to multi-year deals this offseason and each player lines up along the defensive line. Even though Buffalo has an elite team on both sides of the ball, the Bills will have to run through the AFC East if they want any shot of grabbing 12 wins. There's little reason to believe they won't after posting a 5-1 divisional record in 2021. Backing the over here is the best bet.

Bet – Bills: Over 11.5 Wins (-115)

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Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.