Colts vs Steelers Predictions and Expert Picks for Week 16 NFL Game

It's hard to imagine an 11-win Pittsburgh Steelers team as Week 16 home underdogs, but that just goes to show you the way these two franchises have been playing lately. The challenger is of course the Indianapolis Colts, who are a 10-win team in their own right.

In terms of the AFC playoff picture, this could be the most crucial game of the entire week. The results could affect two division winners, playoff seeding for multiple teams, and any perennial Super Bowl runs. To unpack all of this, we'll turn things over to a panel of NFL experts.

Colts vs Steelers Picks Week 16

CBS Sports picks are from their panel of experts, numberFire picks are from their NFL game projections, Sporting News picks are from Vinnie Iyer and betting favorites are from FanDuel Sportsbook's Week 16 NFL odds.

Winner:
CBS Sports: Colts (3), Steelers (1)
numberFire: Colts
Sporting News: Colts
Betting Favorite: Colts -1.5

Against the Spread:
CBS Sports: Colts (3), Steelers (1)
Sporting News: Colts

Based on recent trends and overall form, the experts are mostly rolling with Indy on the road. Pete Prisco of CBS is the lone expert to take Pittsburgh to rebound here at home.

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Michael Obermuller is not a FanDuel employee. In addition to providing DFS gameplay advice, Michael Obermuller also participates in DFS contests on FanDuel using his personal account, username king_mizzard. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.